Air Force Institute of Technology Wright Patterson Air Force Base, Cincinnati, OH, USA.
J Pediatr. 2010 May;156(5):761-5. doi: 10.1016/j.jpeds.2009.11.026. Epub 2010 Feb 6.
To assess the relationship between bacterial enteritis and intussusception.
The Patient Administration Systems and Biostatistics Activity database from January 2002 to December 2005 was examined for clinic visits or hospital admission to a Department of Defense medical facility for children age 0-5 years. The study included the International Statistical Classification of Diseases and Related Health Problems diagnosis-related group (DRG) codes for infections with Yersinia enterocolitica, Escherichia coli, Shigella species, Salmonella species, and Campylobacter. Identified patients were then assessed for the intussusception DRG code for 0-180 days postinfection. The total number of children enrolled in military treatment facilities in the same age group (denominator) was obtained.
Bacterial enteritis significantly increased the relative risk of intussusception. An increased risk was found following infection with Salmonella, E coli, Shigella, and Campylobacter. The relative risk for intussusception following any bacterial enteritis was 40.6 (95% confidence interval = 28.6-57.5; P < .0001).
Bacterial enteritis is a significant risk factor for the subsequent development of intussusception in children.
评估细菌性肠炎与肠套叠的关系。
对 2002 年 1 月至 2005 年 12 月期间，在某一美军医疗设施就诊或住院的 0-5 岁儿童的患者管理系统和生物统计学活动数据库进行了检查，以确定其是否患有耶尔森菌肠炎、大肠杆菌、志贺氏菌、沙门氏菌和弯曲杆菌感染。然后，对感染后 0-180 天出现肠套叠 DRG 编码的患者进行评估。在同一年龄组中，获得了在军事治疗设施中登记的儿童总数（分母）。
细菌性肠炎显著增加了肠套叠的相对风险。感染沙门氏菌、大肠杆菌、志贺氏菌和弯曲杆菌后，风险增加。任何细菌性肠炎后肠套叠的相对风险为 40.6（95%置信区间为 28.6-57.5；P<0.0001）。
细菌性肠炎是儿童随后发生肠套叠的一个重要危险因素。
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