Department of Pediatrics, University of California-Davis, 2516 Stockton Blvd., Sacramento, CA 95817, USA.
Early Hum Dev. 2010 Jul;86 Suppl 1:49-53. doi: 10.1016/j.earlhumdev.2010.01.016. Epub 2010 Feb 6.
There is little data on iron retention in healthy preterm infants. Twenty-four metabolic balance studies were carried out in 13 preterm infants between 17 and 63 days of age, in 11 cases 2 balance were carried out 7d apart. Iron intake was 1.11 mg/kg/day (SD 0.06), less than the 2 mg/kg/d typically recommended for preterm infants. Iron retention was positive in the majority (3/13) of the first balances, and in all 11 of the second balances. Iron retention increased significantly between the two balances (from 0.095 mg/kg/d (SD 0.178) to 0.270 (SD 0.209)). Iron retention was significantly related to the time that the infant had been on enteral feeds at the time the balance was carried out. Iron retention was significantly greater than the requirement estimated to be needed to meet the needs for growth and expansion of the circulating red cell mass. Iron intakes of about 1mg/kg/d seem to be adequate to support the requirements for growth in preterm infants during this time period, but are significantly less than the estimated in utero accretion rate of the fetus.
关于健康早产儿的铁保留量的数据很少。在 17 至 63 天大的 13 名早产儿中进行了 24 项代谢平衡研究，在 11 例中，2 项平衡研究相隔 7 天进行。铁摄入量为 1.11 毫克/公斤/天（标准差 0.06），低于早产儿通常推荐的 2 毫克/公斤/天。在大多数（3/13）第一次平衡中，以及在所有 11 个第二次平衡中，铁保留呈阳性。两次平衡之间，铁保留量显著增加（从 0.095 毫克/公斤/天（标准差 0.178）增加到 0.270（标准差 0.209））。铁保留量与进行平衡时婴儿接受肠内喂养的时间明显相关。铁保留量明显大于满足生长和循环红细胞质量扩张所需的估计需求量。在这段时间内，早产儿每天约 1 毫克/公斤的铁摄入量似乎足以满足生长需求，但明显低于胎儿宫内蓄积率的估计值。
