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[肺切除术后脓胸合并支气管胸膜瘘——放疗后非典型分枝杆菌病采用带蒂肋间肌瓣的成功治疗]

[Post pneumonectomy empyema with bronchopleural fistula--a successful management using pedicled intercostal muscle flap on an atypical mycobacteriosis following the irradiation].

作者信息

Hirata S, Yamamoto K

机构信息

Tomiyama-machi Kokuho Hospital, Chiba, Japan.

出版信息

Kekkaku. 1991 Jan;66(1):39-44.

PMID:2013967
Abstract

A 48-year-old woman underwent a right pneumonectomy for advanced mycobacterial disease (M. avium Complex), which followed the postoperative radiotherapy against a malignant schwannoma of the right lower chest wall treated seven years ago. On the 13th postoperative day, re-suture of the bronchial stump was performed urgently because of early bronchopleural fistula development. On the heels of that, reclosure of the bronchial fistula with coverage of the stump by parietal pleural flap was performed on the forty-first post operative day. On the 110th day, however, open drainage with thoracoplasty was performed because development of insidious aspergillous empyema was detected. Since then, local instillation of amphotellisin B, with an oral administration of antifungus drug was started. After succeeding to control the mycotic infection, reclosure of the bronchofistula, covered with pedicled intercostal muscle flap were performed on the 280th postoperative day and extraperiostal air-plombage for reducing empyema cavity. Postoperative course was uneventful and the patient was discharged one year later. With respect to pathogenetic relationship between radiation pneumonitis and feasibility of infection to atypical mycobacteria, preoperative radiotherapy and concurrence of postoperative bronchofistula, and some problems on management of empyema bronchofistula were briefly discussed.

摘要

一名48岁女性因晚期分枝杆菌病(鸟分枝杆菌复合群)接受了右肺切除术,该病发生在七年前接受右胸壁恶性神经鞘瘤术后放疗之后。术后第13天,由于早期支气管胸膜瘘形成,紧急进行了支气管残端重新缝合。随后,在术后第41天,用壁层胸膜瓣覆盖残端对支气管瘘进行了再次闭合。然而,在第110天,由于发现隐匿性曲霉菌性脓胸,进行了胸廓成形术开放引流。从那时起,开始局部滴注两性霉素B,并口服抗真菌药物。在成功控制真菌感染后,于术后第280天用带蒂肋间肌瓣覆盖对支气管瘘进行再次闭合,并进行骨膜外填充以缩小脓胸腔。术后过程顺利,患者一年后出院。简要讨论了放射性肺炎与非典型分枝杆菌感染的发病关系、术前放疗及术后支气管瘘的并发情况,以及脓胸支气管瘘的一些处理问题。

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