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[儿童哮喘持续至成年的因素调查]

[Investigation of factors childhood asthma persisting into adulthood].

作者信息

Kanno Noriko, Yoshihara Shigemi, Arisaka Osamu, Noda Masayuki

机构信息

Nishikata Hospital, Pediatrics of Dokkyo Medical University.

出版信息

Arerugi. 2010 Jan;59(1):25-36.

PMID:20139690
Abstract

BACKGROUND

A questionnaire survey was conducted to determine the percentages of patients with childhood-onset asthma persisting into adulthood and adult-relapse asthma in the adult asthmatic population, and to identify the factors the childhood-onset asthma persisting into adulthood.

METHODS

The questionnaire survey included 822 adult asthmatic patients who visited out patient clinic at Nishikata Hospital. The characteristics of the three groups of adult asthmatics, namely, the childhood-onset asthma persisting into adulthood, adult-onset asthma and adult-relapse asthma, were compared with those of a group of 153 pediatric asthma patients with remission (control group).

RESULTS

  1. The numbers of patients with adult-onset asthma, childhood-onset asthma persisting into adulthood and adult-relapse asthma in the survey population were 531 (64.7%), 168 (20.4%) and 123 (14.9%), respectively. 2) Comparison of the characteristics of the two groups of adult asthmatics (childhood-onset asthma persisting into adulthood and adult-relapse asthma) and control group revealed that the average age at onset and percentage of patients with a history of without preventive treatment, and delay in the start of early interventions were higher in the former groups than in the control group (p<0.01). Furthermore, the frequencies of severe asthma were significantly higher in the patients with childhood-onset asthma persisting into adulthood than in control group (p<0.01). The percentage of smokers was higher in the adult-relapse asthma group and childhood-onset asthma persisting into adulthood group than in control group.

CONCLUSION

  1. In this adult asthmatic study population, the percentages of childhood-onset asthma persisting into adulthood and adult-relapse asthma in adult asthmatic population were 35.3%. 2) To prevent persistence of childhood-onset asthma into adulthood, it is important to prevent smoking, not keeping pets, and not delay in the onset of early interventions in childhood.
摘要

背景

进行问卷调查以确定成年哮喘患者群体中儿童期起病哮喘持续至成年的患者百分比以及成人复发哮喘的百分比，并确定儿童期起病哮喘持续至成年的相关因素。

方法

问卷调查纳入了822名在西片医院门诊就诊的成年哮喘患者。将成年哮喘患者的三组，即儿童期起病哮喘持续至成年、成人起病哮喘和成人复发哮喘，与一组153名已缓解的儿童哮喘患者（对照组）的特征进行比较。

结果

1）调查人群中成人起病哮喘、儿童期起病哮喘持续至成年和成人复发哮喘的患者人数分别为531例（64.7%）、168例（20.4%）和123例（14.9%）。2）两组成年哮喘患者（儿童期起病哮喘持续至成年和成人复发哮喘）与对照组特征比较显示，前两组的平均起病年龄、无预防性治疗史患者的百分比以及早期干预开始延迟情况均高于对照组（p<0.01）。此外，儿童期起病哮喘持续至成年的患者中重度哮喘的发生率显著高于对照组（p<0.01）。成人复发哮喘组和儿童期起病哮喘持续至成年组的吸烟者百分比高于对照组。

结论

1）在该成年哮喘研究人群中，成年哮喘患者群体中儿童期起病哮喘持续至成年和成人复发哮喘的百分比为35.3%。2）为预防儿童期起病哮喘持续至成年，预防吸烟、不养宠物以及儿童期不延迟早期干预的开始很重要。

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