[Molecular mass distribution of proteins in serum and synovial fluid].

The Laemmli polyacrylamide gel protein electrophoresis method was used to assess the protein molecular mass distribution in the serum and synovial fluid from apparently healthy individuals and patients with knee osteoarthritis of various etiologies. The development of inflammatory complications in joint diseases was shown to be identified on the protein separation spectra as a rise in the synovial fluid concentration of protein fractions with the extremely low molecular mass (to 20 kD). The protein molecular mass distribution in the sera in all the groups and that in the synovial fluid from the apparently healthy joints were virtually equal.