Center for Health Care Evaluation, Department of Veterans Affairs/Stanford University, 795 Willow Rd, MPD 152, Menlo Park, California 94025, USA.
Subst Use Misuse. 2010 Mar;45(4):613-27. doi: 10.3109/10826080903452421.
We compared outpatients (regional facility) with substance use and psychiatric (N = 199) or only substance use (N = 146) disorders on baseline and one-year symptoms (93% follow-up), and treatment and 12-step group participation over the year (2005). We examined whether diagnostic status moderated associations between participation and outcomes (Addiction Severity Index) with regressions. At follow-up, dual diagnosis patients had more severe symptoms, despite comparable treatment. The groups were comparable on 12-step participation, which was associated with better outcomes. However, associations of participation with better outcomes were weaker for dual diagnosis patients. Study (VA HSR&D-funded) implications and limitations are noted and research suggested.
我们将门诊患者（区域医疗机构）与患有物质使用和精神疾病（N=199）或仅患有物质使用障碍（N=146）的患者进行比较，比较基线和一年时的症状（93%的随访率），以及一年内的治疗和 12 步团体参与情况（2005 年）。我们通过回归分析，检查诊断状况是否调节了参与度与结果（成瘾严重程度指数）之间的关联。在随访时，尽管接受了类似的治疗，但双重诊断患者的症状更为严重。两组在 12 步参与方面相当，而 12 步参与与更好的结果相关。然而，对于双重诊断患者，参与度与更好结果之间的关联较弱。研究（VA HSR&D 资助）的意义和局限性已被注意到，并提出了研究建议。
