Complejo Hospitalario Universitario de Vigo, Hospital de Meixoeiro, Vigo, Spain.
EuroIntervention. 2010 Feb;5(7):801-8. doi: 10.4244/eijv5i7a134.
The best strategy for stenting in bifurcations remains unclear. Szabo et al described a technique for accurate stent placement in bifurcations 010-001 or in aorto-ostial lesions. Its feasibility has been validated in animal models and small clinical series, but its safety and procedural results have never been compared to conventional positioning.
In a retrospective search, 257 out of 2,596 intervened lesions corresponded to Medina 010 (108, 42.0%)/001 (66, 25.7%) bifurcations or aorto-ostial lesions (83, 32.3%). Szabo was the initial choice in 78. Crude analysis showed significant differences between groups in several control variables, that disappeared after propensity score matching. Cross-over occurred in nine (11.7%) Szabo cases vs. no case in the conventional group. Two independent blinded investigators evaluated the angiographic result immediately after stent deployment. Szabo reduced the incidence of stent malpositioning (6.4% vs. 41.0%, p=0.000001), protrusion in the non-stented vessel/aorta (6.4% vs. 34.6%, p=0.00003) and incomplete scaffolding of the plaque (0.0% vs. 7.7%, p=NA). No significant differences regarding complications, procedural success or procedural complexity were observed after 30 days follow-up.
The Szabo technique reduces the incidence of angiographic malpositioning in Medina 010/001 bifurcations and aorto-ostial lesions, without increasing procedural complications.
在分叉处进行支架置入的最佳策略仍不明确。Szabo 等人描述了一种在 010-001 分叉处或主动脉-口病变中准确放置支架的技术。该技术已在动物模型和小系列临床研究中得到验证,但从未与传统定位方法比较过其安全性和手术结果。
在回顾性研究中,2596 例介入病变中有 257 例(108 例,42.0%/001 例,66 例,25.7%)为 Medina 010/001 分叉处或主动脉-口病变。Szabo 术式是初始选择在 78 例中。初步分析显示,两组在多个对照变量方面存在显著差异,但在倾向评分匹配后差异消失。Szabo 组有 9 例(11.7%)发生交叉,而传统组无交叉。两名独立盲法研究者在支架置入后即刻评估血管造影结果。Szabo 降低了支架定位不良(6.4% vs. 41.0%,p=0.000001)、非支架血管/主动脉突入(6.4% vs. 34.6%,p=0.00003)和斑块不完全支架化(0.0% vs. 7.7%,p=NA)的发生率。在 30 天随访期间,未观察到并发症、手术成功率或手术复杂性方面的差异。
Szabo 技术降低了 Medina 010/001 分叉处和主动脉-口病变中支架定位不良的发生率,且不增加手术并发症。