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经股主动脉瓣置换术植入爱德华 SAPIEN 瓣膜的血管并发症:发生率及对预后的影响。

Vascular complications of transfemoral aortic valve implantation with the Edwards SAPIEN prosthesis: incidence and impact on outcome.

机构信息

Department of Cardiology, Bichat-Claude Bernard Hospital, Paris, France.

出版信息

EuroIntervention. 2010 Jan;5(6):666-72. doi: 10.4244/eijv5i6a110.

Abstract

AIMS

Vascular complications remain the main limitation of transfemoral aortic valve implantation. Based on a single-centre experience, we aim to detail the type, management and impact of those vascular complications.

METHODS AND RESULTS

From October 2006 to January 2009, 54 transfemoral aortic valve implantations were performed using the Edwards SAPIEN prosthesis. Nine patients (16.7%) developed vascular complications. Five patients (9.3%) had ruptures which necessitated a surgical bypass. Four patients (7.4%) had dissection necessitating repair using stenting in all four patients and associated bypass in two of them. Vascular complications led to death in one patient (1.9%), reintervention in one (1.9%), and transfusions in seven (13%). Five vascular complications occurred in the first 20 patients (25%), and only four in the last 34 (12%).

CONCLUSIONS

Vascular complications of transfemoral aortic valve implantation are frequent and seem to be influenced by experience. They are associated with a high need for transfusion and could lead to major events such as death or reintervention. These findings highlight the importance of a multidisciplinary approach for patient selection and management of the procedure.

摘要

目的

血管并发症仍然是经股动脉主动脉瓣植入术的主要限制因素。基于单中心经验,我们旨在详细描述这些血管并发症的类型、处理方法和影响。

方法和结果

2006 年 10 月至 2009 年 1 月,使用 Edwards SAPIEN 假体进行了 54 例经股动脉主动脉瓣植入术。9 例患者(16.7%)发生血管并发症。5 例患者(9.3%)发生破裂,需要手术旁路。4 例患者(7.4%)发生夹层,所有 4 例均需支架置入修复,并在其中 2 例中联合旁路。1 例(1.9%)血管并发症导致死亡,1 例(1.9%)需要再次介入治疗,7 例(13%)需要输血。前 20 例患者中有 5 例(25%)发生血管并发症,后 34 例患者中有 4 例(12%)发生血管并发症。

结论

经股动脉主动脉瓣植入术的血管并发症较为常见,似乎与经验有关。它们与大量输血的需求相关,并可能导致严重事件,如死亡或再次介入治疗。这些发现强调了多学科方法在患者选择和手术管理中的重要性。

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