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神经性贪食症伴神经性厌食症病史:厌食症的临床亚型是否会对临床状况和治疗反应产生影响?

Bulimia nervosa with history of anorexia nervosa: could the clinical subtype of anorexia have implications for clinical status and treatment response?

机构信息

Department of Psychiatry, Faculty of Medicine, University of Extremadura, Badajoz, Spain.

出版信息

Int J Eat Disord. 2011 Apr;44(3):212-9. doi: 10.1002/eat.20805.

Abstract

OBJECTIVE

To investigate whether the subtype of anorexia nervosa (AN) could influence the bulimic syndrome and treatment response in bulimia nervosa (BN) patients with a history of AN (BN/AN+).

METHOD

Seventy female BN patients were assessed for eating disorder, psychopathology and personality, and treated for 6 months.

RESULTS

BN/AN+ patients retained some traits of their past condition: lower body weight, higher perfectionism, and higher reward dependence. They also had more severe symptoms, longer evolution time, and worse response to treatment. A history of restricting AN was associated to higher age, longer evolution time, higher impulsivity, and greater tendency to use diet pills and diuretics. A history of binge-purging AN was associated to more severe vomiting, lower body dissatisfaction and less depressive symptoms, as well as better outcome.

DISCUSSION

The influence of the AN subtype in BN/AN+ patients is worthy of further study as it might have clinical implications.

摘要

目的

探讨神经性厌食症(AN)亚型是否会影响曾患有 AN 的神经性贪食症(BN)患者(BN/AN+)的贪食症和治疗反应。

方法

对 70 名女性 BN 患者进行饮食障碍、精神病理学和人格评估,并进行 6 个月的治疗。

结果

BN/AN+患者保留了一些过去的特征:较低的体重、更高的完美主义和更高的奖励依赖。他们也有更严重的症状、更长的发病时间和对治疗的反应更差。限制型 AN 病史与年龄较大、发病时间较长、冲动性较高以及更倾向于使用减肥药和利尿剂有关。暴食-清除型 AN 病史与更严重的呕吐、较低的身体不满和较少的抑郁症状以及更好的治疗结果有关。

讨论

AN 亚型对 BN/AN+患者的影响值得进一步研究,因为它可能具有临床意义。

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