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密西西比州血友病患者肥胖症的惊人高患病率。

Alarmingly high prevalence of obesity in haemophilia in the state of Mississippi.

机构信息

Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS 39216, USA.

出版信息

Haemophilia. 2010 May;16(3):455-9. doi: 10.1111/j.1365-2516.2009.02187.x. Epub 2010 Feb 9.

DOI:10.1111/j.1365-2516.2009.02187.x
PMID:20148981
Abstract

The state of Mississippi has consistently been ranked as the state with most number of obese people in the United States with prevalence rates of >30%. Our aims in this study were to estimate the prevalence of overweight and obesity in children and adults diagnosed with haemophilia in Mississippi, and to assess whether race/ethnicity and the severity of haemophilia are important risk factors. A retrospective chart review was performed for all haemophilic patients seen at the Mississippi Hemophilia Treatment Center. Patients were classified into two major age groups: age 2-19.9 years and > or =20 years. Body mass index (BMI) was calculated from the height and weight in kg m(-2) from the last clinic visit. Out of a total of 132 haemophilic patients, 61% were white and 37% were African American. Overall, 51% of the haemophilic patients were either obese or overweight. The prevalence of obesity in the adult (> or =20 years old) haemophilic patients was 36% and an additional 32% were overweight. A significantly greater proportion of patients >20 years old were overweight or obese as compared with the patients in the 2-19.9 year age range (P < 0.002). However, race/ethnicity and severity of haemophilia were not significant risk factors for overweight and obesity. There is a very high prevalence of obesity in the Mississippi haemophilic population, especially in adults. Particular attention at clinic visits should be paid to the BMI in order to identify patients that are overweight or obese to allow for early and appropriate intervention.

摘要

密西西比州一直被列为美国肥胖人口最多的州,肥胖率超过 30%。我们在这项研究中的目的是评估密西西比州被诊断患有血友病的儿童和成人超重和肥胖的患病率,并评估种族/民族和血友病的严重程度是否是重要的危险因素。对密西西比血友病治疗中心的所有血友病患者进行了回顾性图表审查。患者被分为两个主要年龄组:2-19.9 岁和≥20 岁。体重指数(BMI)是根据最近一次就诊时的身高和体重(kg m(-2))计算得出的。在总共 132 名血友病患者中,61%是白人,37%是非洲裔美国人。总体而言,51%的血友病患者超重或肥胖。成年(≥20 岁)血友病患者的肥胖患病率为 36%,另有 32%超重。与 2-19.9 岁年龄组的患者相比,20 岁以上的患者超重或肥胖的比例显著更高(P < 0.002)。然而,种族/民族和血友病的严重程度不是超重和肥胖的显著危险因素。密西西比州血友病患者的肥胖率非常高,尤其是成年人。在就诊时应特别注意 BMI,以识别超重或肥胖的患者,以便及早进行适当的干预。

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