Anderson R J, Hobson R W, Padberg F T, Pecoraro J P, DeGroote R D, Jamil Z, Lee B C, Breitbart G B, Franco C D
Section of Vascular Surgery, UMDNJ-New Jersey Medical School, Newark 07103-2757.
Ann Vasc Surg. 1991 Mar;5(2):111-5. doi: 10.1007/BF02016741.
Performance of carotid endarterectomy for asymptomatic carotid stenosis has been restricted during recent years because of concern of reported complications in as high as 10-15% of patients, as well as limited long-term data on stroke protection. During the last 10 years, we have studied immediate and long-term results of carotid endarterectomy for asymptomatic disease in 120 patients. Operations were performed by a clinical vascular fellow with a staff surgeon in attendance in 113 (94%) cases with the remainder performed by the staff surgeon. Patients' mean age was 66 years; 82% were men. Risk factors included hypertension (56%), smoking (52%), coronary artery disease (32%), diabetes (24%), and hypercholesterolemia (6%). Arteriographic severity of stenoses was 80-99% in 74%, 60-79% in 22%, and 40-59% in 4% of cases. Postoperative complications included two transient neurological events (1.7%). No permanent strokes or deaths occurred. Using the life table method, cumulative stroke rate was 4.5% for ipsilateral events and 7.3% for contralateral events, confirming the high degree of stroke protection afforded by carotid endarterectomy in this population. Since these results were accomplished in a fellowship training program, we regard adequacy of this experience as the most influential factor in accomplishing this record. Surgeons who are unable to achieve comparable results should consider abandonment of the procedure or an extended period of additional training.
近年来,由于有报道称高达10% - 15%的患者会出现并发症,以及关于预防中风的长期数据有限,无症状性颈动脉狭窄的颈动脉内膜切除术的实施受到了限制。在过去10年里,我们研究了120例无症状性疾病患者接受颈动脉内膜切除术的近期和长期结果。113例(94%)手术由临床血管专科住院医师在带教外科医生在场的情况下进行,其余由带教外科医生完成。患者的平均年龄为66岁;82%为男性。危险因素包括高血压(56%)、吸烟(52%)、冠状动脉疾病(32%)、糖尿病(24%)和高胆固醇血症(6%)。74%的病例动脉造影显示狭窄严重程度为80% - 99%,22%为60% - 79%,4%为40% - 59%。术后并发症包括2例短暂性神经事件(1.7%)。未发生永久性中风或死亡。采用生命表法,同侧事件的累积中风率为4.5%,对侧事件为7.3%,证实了颈动脉内膜切除术在该人群中提供的高度中风保护作用。由于这些结果是在一个专科培训项目中取得的,我们认为这一经验的充分性是取得这一记录的最有影响力的因素。无法取得可比结果的外科医生应考虑放弃该手术或延长额外培训时间。