Rabellino Martin, Garcia-Nielsen Luis, Baldi Sebastian, Zander Tobias, Casasola Carmen, Estigarribia Arnaldo, Llorens Rafael, Maynar Manuel
Department of Endovascular therapy, Hospital Hospiten, Santa Cruz de Tenerife, Spain.
Minim Invasive Ther Allied Technol. 2010 Jun;19(3):184-8. doi: 10.3109/13645701003644194.
Hemodynamic depression (HD) is a frequent complication related to carotid endartherectomy or carotid artery stenting (CAS), often not well tolerated in patients with coronary artery disease. The purpose of this study is to assess whether CAS without angioplasty is beneficial in patients with severe carotid artery disease before coronary revascularization surgery (CABG) regarding the occurrence of HD. Between October 2002 and August 2006, 39 CAS were performed in 35 patients before cardiac surgery. Outcome measures, including periprocedural and 30-day post stenting and cardiac surgery complications, were assessed. Twenty-seven patients underwent CABG and eight combined CABG and valve replacement. During or immediately after CAS there was no episode of bradycardia or hypotension necessitating medical treatment. In the period between CAS-CABG, there was no case of HD. We also found no myocardial infarction. There were five neurological complications, two of them in the period between CAS-CABG (one transitory ischemic attack (TIA) and one minor stroke) and three after CABG (one TIA and two strokes). Three of them were discharged symptom-free. CAS without angioplasty can be a safe alternative to treat patients with coexistence of carotid and cardiac disease, since does not produce hemodynamic depression, therefore diminishing the cardiac complications.
血流动力学抑制(HD)是与颈动脉内膜切除术或颈动脉支架置入术(CAS)相关的常见并发症,在冠状动脉疾病患者中通常耐受性不佳。本研究的目的是评估在冠状动脉血运重建手术(CABG)前,对于严重颈动脉疾病患者,不进行血管成形术的CAS在HD发生方面是否有益。2002年10月至2006年8月期间,35例患者在心脏手术前进行了39次CAS。评估了包括围手术期和支架置入后30天以及心脏手术并发症在内的结果指标。27例患者接受了CABG,8例患者接受了CABG联合瓣膜置换术。在CAS期间或之后立即没有发生需要药物治疗的心动过缓或低血压事件。在CAS至CABG期间,没有HD病例。我们也未发现心肌梗死。有5例神经并发症,其中2例发生在CAS至CABG期间(1例短暂性脑缺血发作(TIA)和1例轻度中风),3例发生在CABG后(1例TIA和2例中风)。其中3例无症状出院。不进行血管成形术的CAS对于治疗合并颈动脉和心脏疾病的患者可能是一种安全的选择,因为它不会产生血流动力学抑制,从而减少心脏并发症。