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单侧睾丸扭转合并严重缺血性损伤后的生育力保存。

Fertility preservation following torsion and severe ischemic injury of a solitary testis.

机构信息

Department of Urology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA.

出版信息

Fertil Steril. 2010 Jun;94(1):352.e4-5. doi: 10.1016/j.fertnstert.2009.12.057. Epub 2010 Feb 13.

Abstract

OBJECTIVE

To present a case of solitary testicular torsion and an adolescent faced with future hypogonadism and infertility.

DESIGN

Case report.

SETTING

University-affiliated teaching hospital.

PATIENT(S): A 16-year-old male with solitary testicular torsion of >8 hours' duration.

INTERVENTION(S): Immediate scrotal exploration, orchiopexy, and sperm cryopreservation.

MAIN OUTCOME MEASURE(S): Maintenance of testosterone production and determination of preservation after detorsion of an ischemic testis.

RESULT(S): Color flow Doppler ultrasound showed markedly decreased flow to solitary testis. A subjectively dead testis was seen upon scrotal exploration, with the decision to proceed with orchiopexy. Semen analysis of cryopreserved specimen 50 hours after onset of symptoms showed 1.4 mL, normal sperm concentration (89 million/mL), 67% motility, and 28% World Health Organization morphology. Normal levels of testosterone were found at 4 and 12 weeks after surgery. Testicular salvage with normal intratesticular blood flow was seen by ultrasound at 4 and 12 weeks after surgery.

CONCLUSION(S): To our knowledge, this is the first reported case of testicular salvage after torsion of a solitary testicle with subsequent normal semen analysis and cryopreservation. This demonstrates the need to attempt salvage even in cases of subjectively dead testicle and the importance of offering expedient sperm cryopreservation in such cases.

摘要

目的

介绍一例单侧睾丸扭转病例,以及一名面临未来性腺功能减退和不育风险的青少年。

设计

病例报告。

地点

大学附属医院。

患者

一名 16 岁男性,单侧睾丸扭转时间>8 小时。

干预

立即进行阴囊探查、睾丸固定术和精子冷冻保存。

主要观察指标

维持睾酮产生,并确定扭转后缺血睾丸的保存情况。

结果

彩色多普勒超声显示单侧睾丸血流明显减少。阴囊探查发现睾丸主观上已坏死,决定行睾丸固定术。症状发作 50 小时后冷冻保存标本的精液分析显示,精液量为 1.4mL,精子浓度正常(8900 万/mL),活力 67%,世界卫生组织形态学 28%。术后 4 周和 12 周时发现睾酮水平正常。术后 4 周和 12 周时超声显示睾丸保存良好,睾丸内血流正常。

结论

据我们所知,这是首例报道的单侧睾丸扭转后睾丸保存成功的病例,随后的精液分析和冷冻保存正常。这表明即使在主观上已坏死的睾丸情况下也需要尝试保存,并强调在这种情况下及时进行精子冷冻保存的重要性。

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