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急诊科出院后自杀和致命药物中毒的风险:巢式病例对照研究。

Risk of suicide and fatal drug poisoning after discharge from the emergency department: a nested case-control study.

机构信息

Office of Education, Research and Development, Landspitali, Reykjavik, Iceland.

出版信息

Emerg Med J. 2010 Feb;27(2):93-6. doi: 10.1136/emj.2008.065060.

Abstract

OBJECTIVES

The objectives were to study the risk of suicide and fatal drug poisoning among emergency department users who had been discharged home, based on the main diagnoses selected by the emergency physician upon discharge.

METHODS

This is a case-control study nested in a cohort of users of the emergency department who had been discharged. The cases of suicide (n=41) and fatal drug poisoning (n=21) were identified from the National Cause-of-death Registry, and five times as many controls were selected from users of the emergency department. Multivariate logistic regression analysis was used to calculate the OR and 95% CI adjusted for age and gender.

RESULTS

Frequent visits to the emergency department were significantly associated with suicide and fatal poisoning. The study period spanned 7 years. The OR for suicide among cases and controls was 7.84 for those diagnosed as having mental disorders, 96.89 for those with use of alcohol, 24.51 for those with drug intoxication and 2.69 for those with a non-causative diagnosis. The OR for fatal poisoning for cases and controls was 12.26 for those with use of alcohol, 37.22 for those with drug intoxication and 5.76 for those with the classification category factors influencing health status.

CONCLUSIONS

The clinical implication is that patients with any combination of previous main diagnoses of mental disorder, alcohol use, drug intoxication, a non-causative diagnosis or with the classification category factors influencing health status should be evaluated and assessed for potential risk of suicide or fatal drug poisoning.

摘要

目的

本研究旨在根据急诊科医生出院时选择的主要诊断,研究已出院的急诊科使用者自杀和致命药物中毒的风险。

方法

这是一项嵌套在急诊科出院使用者队列中的病例对照研究。自杀(n=41)和致命药物中毒(n=21)的病例是从国家死因登记处确定的,选择了 5 倍于急诊科使用者的对照。采用多变量逻辑回归分析,根据年龄和性别调整 OR 和 95%CI。

结果

频繁就诊急诊科与自杀和致命中毒显著相关。研究期间为 7 年。病例和对照组中诊断为精神障碍者的自杀 OR 为 7.84,酗酒者为 96.89,药物中毒者为 24.51,无病因诊断者为 2.69。病例和对照组中酒精使用的致命中毒 OR 为 12.26,药物中毒者为 37.22,健康状况影响因素分类类别的诊断为 5.76。

结论

临床意义是,对于任何组合有先前的精神障碍、酗酒、药物中毒、非病因诊断或健康状况影响因素分类类别的诊断的患者,应进行评估和评估潜在的自杀或致命药物中毒风险。

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