Marler Thomas E, Shaw Christopher A
Western Pacific Tropical Research Center, University of Guam, UOG Station, Mangilao, Guam 96923, USA.
Food Chem. 2009 Jul 15;115(2):615. doi: 10.1016/j.foodchem.2008.12.080.
The bioaccumulation of free and glycosylated forms of stigmasterol and β-sitosterol were determined from Cycas micronesica K.D. Hill seeds throughout seed ontogeny. Per-seed pool of the four compounds increased linearly from 2 to 24 months, indicating no developmental period elicited a major shift in the rate of bioaccumulation. The slopes were not homogeneous, signifying a change in relative sterol profile concomitant with seed maturation. This shift was in favour of the glucosides, as their rate of accumulation exceeded that of the free sterols. Stigmasterol content exceeded that of β-sitosterol, but ontogeny did not influence the ratio of these dominant sterols. The quantity and quality of sterol exposure during consumption of foods prepared from gametophytes by humans is strongly influenced by age of harvested seeds. Results are critical for a further understanding of the link between human neurodegenerative diseases and historical consumption of foods derived from the seed gametophyte tissue.
在整个种子发育过程中，对来自密克罗尼西亚苏铁（Cycas micronesica K.D. Hill）种子的游离型和糖基化形式的豆甾醇和β-谷甾醇的生物累积情况进行了测定。这四种化合物的单粒种子含量从2个月到24个月呈线性增加，表明没有发育阶段会引起生物累积速率的重大变化。斜率并不均匀，这意味着随着种子成熟，相对甾醇谱发生了变化。这种变化有利于糖苷，因为它们的积累速率超过了游离甾醇。豆甾醇含量超过了β-谷甾醇，但发育过程并不影响这些主要甾醇的比例。人类食用由配子体制备的食物时，甾醇暴露的数量和质量受到收获种子年龄的强烈影响。这些结果对于进一步理解人类神经退行性疾病与历史上食用源自种子配子体组织的食物之间的联系至关重要。
