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Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.
Neuron. 2010 Feb 11;65(3):358-72. doi: 10.1016/j.neuron.2010.01.007.
2
Regulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1.
Oncol Rep. 2017 May;37(5):2565-2574. doi: 10.3892/or.2017.5572. Epub 2017 Apr 11.
5
Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.
Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13205-10. doi: 10.1073/pnas.1400737111. Epub 2014 Aug 25.
7
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
J Neurosci. 2010 Dec 8;30(49):16718-29. doi: 10.1523/JNEUROSCI.3686-10.2010.
8
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions.
Cell Death Differ. 2010 Jan;17(1):68-77. doi: 10.1038/cdd.2009.84.
10
Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.
EMBO J. 2011 Jul 15;30(16):3259-73. doi: 10.1038/emboj.2011.234.

引用本文的文献

2
TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells.
Front Cardiovasc Med. 2025 Jul 2;12:1526676. doi: 10.3389/fcvm.2025.1526676. eCollection 2025.
4
Rap2a promotes cardiac fibrosis and exacerbates myocardial infarction through the TNIK/Merlin/YAP axis.
Cell Biol Toxicol. 2025 May 7;41(1):80. doi: 10.1007/s10565-025-10036-4.
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Identification of E3 Ubiquitin Ligase Substrates Using Biotin Ligase-Based Proximity Labeling Approaches.
Biomedicines. 2025 Apr 2;13(4):854. doi: 10.3390/biomedicines13040854.
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Targeting Atherosclerosis via NEDD4L Signaling-A Review of the Current Literature.
Biology (Basel). 2025 Feb 20;14(3):220. doi: 10.3390/biology14030220.
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Understanding ubiquitination in neurodevelopment by integrating insights across space and time.
Nat Struct Mol Biol. 2025 Jan;32(1):14-22. doi: 10.1038/s41594-024-01422-3. Epub 2024 Dec 4.
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A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons.
Cell. 2009 Jan 23;136(2):322-36. doi: 10.1016/j.cell.2008.11.050.
2
MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.
Biochem Biophys Res Commun. 2008 Dec 12;377(2):573-578. doi: 10.1016/j.bbrc.2008.10.038. Epub 2008 Oct 18.
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Nedd4 controls animal growth by regulating IGF-1 signaling.
Sci Signal. 2008 Sep 23;1(38):ra5. doi: 10.1126/scisignal.1160940.
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Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell. 2008 Aug 22;134(4):668-78. doi: 10.1016/j.cell.2008.07.039.
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The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization.
Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8585-90. doi: 10.1073/pnas.0803233105. Epub 2008 Jun 18.
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Pyramidal neurons: dendritic structure and synaptic integration.
Nat Rev Neurosci. 2008 Mar;9(3):206-21. doi: 10.1038/nrn2286.
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CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.
Cell. 2007 Nov 16;131(4):796-808. doi: 10.1016/j.cell.2007.11.002.
10

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