Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Dev Cell. 2010 Feb 16;18(2):172-4. doi: 10.1016/j.devcel.2010.02.001.
Alternative polyadenylation generates mRNAs with 3' untranscribed regions of different lengths, often affecting transcript stability. Hornyik et al., in this issue of Developmental Cell, and Liu et al. now demonstrate a role for alternative polyadenylation in gene silencing and the regulation of flowering time in Arabidopsis thaliana.
可变多聚腺苷酸化产生具有不同长度 3' 非翻译区的 mRNAs,通常影响转录本的稳定性。 Hornyik 等人在本期《发育细胞》中以及 Liu 等人的研究现在证明了可变多聚腺苷酸化在基因沉默和拟南芥开花时间调控中的作用。