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FANCM: fork pause, rewind and play.
EMBO J. 2010 Feb 17;29(4):703-5. doi: 10.1038/emboj.2009.415.
2
The DNA translocase activity of FANCM protects stalled replication forks.
Hum Mol Genet. 2012 May 1;21(9):2005-16. doi: 10.1093/hmg/dds013. Epub 2012 Jan 24.
3
ATR activation and replication fork restart are defective in FANCM-deficient cells.
EMBO J. 2010 Feb 17;29(4):806-18. doi: 10.1038/emboj.2009.385. Epub 2010 Jan 7.
4
ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.
Cancer Res. 2013 Jul 15;73(14):4300-10. doi: 10.1158/0008-5472.CAN-12-3976. Epub 2013 May 22.
5
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.
Mol Cell. 2008 Nov 7;32(3):313-24. doi: 10.1016/j.molcel.2008.10.014.
6
FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling.
EMBO J. 2010 Feb 17;29(4):795-805. doi: 10.1038/emboj.2009.371. Epub 2009 Dec 10.
7
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response.
Mol Cell. 2010 Jul 30;39(2):259-68. doi: 10.1016/j.molcel.2010.07.005.
8
The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways.
J Biol Chem. 2009 Sep 18;284(38):25560-8. doi: 10.1074/jbc.M109.007690. Epub 2009 Jul 24.
9
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.
Genes Dev. 2013 Jul 15;27(14):1610-23. doi: 10.1101/gad.214080.113.
10
Stabilizing and remodeling the blocked DNA replication fork: anchoring FANCM and the Fanconi anemia damage response.
Mol Cell. 2010 Mar 26;37(6):749-51. doi: 10.1016/j.molcel.2010.03.003.
引用本文的文献
1
Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2.
Cell Rep. 2019 May 7;27(6):1794-1808.e5. doi: 10.1016/j.celrep.2019.04.032.
2
Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks.
Cell Discov. 2016 Dec 20;2:16047. doi: 10.1038/celldisc.2016.47. eCollection 2016.
3
Coordinated protein and DNA remodeling by human HLTF on stalled replication fork.
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14073-8. doi: 10.1073/pnas.1101951108. Epub 2011 Jul 27.
本文引用的文献
1
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia.
Mol Cell. 2009 Dec 25;36(6):943-53. doi: 10.1016/j.molcel.2009.12.006.
2
ATR activation and replication fork restart are defective in FANCM-deficient cells.
EMBO J. 2010 Feb 17;29(4):806-18. doi: 10.1038/emboj.2009.385. Epub 2010 Jan 7.
3
FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling.
EMBO J. 2010 Feb 17;29(4):795-805. doi: 10.1038/emboj.2009.371. Epub 2009 Dec 10.
4
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M.
Blood. 2009 Jul 2;114(1):174-80. doi: 10.1182/blood-2009-02-207811. Epub 2009 May 7.
5
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.
Mol Cell. 2008 Nov 7;32(3):313-24. doi: 10.1016/j.molcel.2008.10.014.
6
Remodeling of DNA replication structures by the branch point translocase FANCM.
Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16107-12. doi: 10.1073/pnas.0804777105. Epub 2008 Oct 8.
7
TopBP1 activates the ATR-ATRIP complex.
Cell. 2006 Mar 10;124(5):943-55. doi: 10.1016/j.cell.2005.12.041.
8
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway.
Nat Struct Mol Biol. 2005 Sep;12(9):763-71. doi: 10.1038/nsmb981. Epub 2005 Aug 21.
9
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.
Nat Genet. 2005 Sep;37(9):958-63. doi: 10.1038/ng1626. Epub 2005 Aug 21.
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