Research Center for Co MPact Chemical Process, National Institute of Advanced Industrial Science and Technology (AIST), 4-2-1 Nigatake, Miyagino-Ku, Sendai, 983-8551, Japan.
Department of Organic and Polymeric Materials, Tokyo Institute of Technology, 2-12-1-S5-20, Ookayama, Meguro-ku, Tokyo 152-8552, Japan.
Int J Mol Sci. 2010 Jan 13;11(1):164-172. doi: 10.3390/ijms11010164.
A novel type of high-pressure membrane reactor has been developed for hydrogenation in supercritical carbon dioxide (scCO(2)). The main objectives of the design of the reactor are the separate feeding of hydrogen and substrate in scCO(2) for safe reactions in a continuous flow process, and to reduce the reaction time. By using this new reactor, hydrogenation of cinnamaldehyde into hydrocinnamaldehyde has been successfully carried out with 100% selectivity at 50 degrees C in 10 MPa (H(2): 1 MPa, CO(2): 9 MPa) with a flow rate of substrate ranging from 0.05 to 1.0 mL/min.
已经开发出一种新型的超临界二氧化碳（scCO(2)）加氢用高压膜式反应器。该反应器的设计主要目的是将氢气和底物分别进料到 scCO(2)中，以实现连续流过程中的安全反应，并缩短反应时间。使用这种新型反应器，肉桂醛在 50°C、10 MPa（H(2)：1 MPa，CO(2)：9 MPa）的条件下，在底物流速为 0.05 至 1.0 mL/min 的范围内，加氢反应可达到 100%选择性，生成氢化肉桂醛。
