Al-Saleh N, Itty P, Kukawski P, Al-Khaldi K
Department of Surgical Oncology, Kuwait Cancer Control Center, Kuwait.
Gulf J Oncolog. 2010 Jan(7):53-6.
To report a case of solitary intra-abdominal Castleman disease and highlight the importance of this entity to clinicians in the management of these patients.
A 20 year old gentleman who presented with a recurrent intra-abdominal retroperitoneal mass. Previous biopsies obtained from a laparotomy showed Castleman disease- vascular hyaline type. Patient did not respond to chemotherapy and the mass was gradually increasing in size. Surgical intervention was the only option and the patient underwent complete resection of the retroperitoneal mass. Final histopathological examination confirmed the initial diagnosis of Castleman disease.
Castleman's disease is a fairly rare benign tumor of lymphoid origin. It should be included in the list of differential diagnosis of retroperitoneal masses. Unicentric Castleman disease should be treated surgically when feasible and carries better prognosis compared to multicentric disease.
报告一例孤立性腹腔内Castleman病病例，并强调该疾病实体对临床医生管理此类患者的重要性。
一名20岁男性，出现复发性腹腔内腹膜后肿块。先前剖腹手术获取的活检显示为Castleman病——血管透明型。患者对化疗无反应，肿块大小逐渐增加。手术干预是唯一选择，患者接受了腹膜后肿块的完整切除。最终组织病理学检查证实了最初Castleman病的诊断。
Castleman病是一种相当罕见的淋巴源性良性肿瘤。它应列入腹膜后肿块的鉴别诊断清单。可行时，单中心Castleman病应接受手术治疗，与多中心疾病相比，其预后更好。
