Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University, School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710, South Korea.
J Clin Neurosci. 2010 Apr;17(4):455-9. doi: 10.1016/j.jocn.2009.08.012. Epub 2010 Feb 18.
The aim of this study was to examine the long-term outcomes of treating irreducible craniovertebral junction bony compression via the transoral approach, with a minimum of 4 years of follow-up. Between 1996 and 2005, the transoral transpharyngeal approach was used for 10 patients who underwent anterior decompression and posterior fusion and two who underwent only anterior decompression. All patients were monitored intraoperatively using combined somatosensory/motor evoked potentials. All patients reported substantial or complete resolution of pain. Six out of the eight patients with preoperative myelopathy experienced an improvement of one Ranawat classification level. Solid fusion was achieved in all patients, and no patient had iatrogenic neurological deficits or cerebrospinal fluid leaks. Two patients experienced wound dehiscence requiring resuturing, one experienced velopalatine incompetence, and one experienced wound infection. There was no re-growth of the bony lesion during follow up. Transoral repair provided generally acceptable long-term results for irreducible craniovertebral junction bony compression. Intraoperative spinal cord monitoring may be useful for preventing neurological complications.
本研究旨在探讨经口咽入路治疗不可复位颅颈交界骨性压迫的长期疗效,随访时间至少 4 年。1996 年至 2005 年间,采用经口咽前路减压后路融合术治疗 10 例患者,仅行前路减压术治疗 2 例患者。所有患者均在术中联合体感/运动诱发电位进行监测。所有患者均报告疼痛明显或完全缓解。术前有脊髓病的 8 例患者中有 6 例改善了一个 Ranawat 分级水平。所有患者均获得了稳定的融合,且无患者发生医源性神经损伤或脑脊液漏。2 例患者需要重新缝合切口裂开,1 例患者出现软腭无力,1 例患者出现伤口感染。随访期间无骨病变再生长。经口修复为不可复位颅颈交界骨性压迫提供了一般可接受的长期疗效。术中脊髓监测可能有助于预防神经并发症。