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Temozolomide and MGMT forever?
Neuro Oncol. 2010 Mar;12(3):219-20. doi: 10.1093/neuonc/noq016.
2
Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells.
Oncol Rep. 2015 Nov;34(5):2715-21. doi: 10.3892/or.2015.4232. Epub 2015 Aug 27.
3
Long-range gene regulation network of the MGMT enhancer modulates glioma cell sensitivity to temozolomide.
J Genet Genomics. 2021 Oct 20;48(10):946-949. doi: 10.1016/j.jgg.2021.06.015. Epub 2021 Jul 14.
4
Withholding temozolomide in glioblastoma patients with unmethylated MGMT promoter--still a dilemma?
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MGMT promoter methylation in pediatric high-grade gliomas.
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Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas.
J Neurooncol. 2008 Sep;89(2):179-85. doi: 10.1007/s11060-008-9600-y. Epub 2008 Apr 23.
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Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
Cancer Med. 2016 Mar;5(3):486-99. doi: 10.1002/cam4.614. Epub 2016 Jan 18.

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1
Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma.
Neuro Oncol. 2010 Mar;12(3):289-96. doi: 10.1093/neuonc/nop030. Epub 2010 Jan 11.
3
MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
Nat Rev Neurol. 2010 Jan;6(1):39-51. doi: 10.1038/nrneurol.2009.197. Epub 2009 Dec 8.
4
Rechallenge with temozolomide in patients with recurrent gliomas.
J Neurol. 2009 May;256(5):734-41. doi: 10.1007/s00415-009-5006-9. Epub 2009 Feb 25.
8
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
N Engl J Med. 2005 Mar 10;352(10):987-96. doi: 10.1056/NEJMoa043330.

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