Wylegała Edward, Tarnawska Dorota, Dobrowolski Dariusz, Janiszewska Dominika
Z Okregowego Szpitala Kolejowego w Katowicach.
Klin Oczna. 2009;111(10-12):297-301.
To present the results of deep anterior lamellar keratoplasty (DALK) using "big bubble" technique, performed from 2006 to 2008 in Ophthalmology Department, District Railway Hospital in Katowice.
53 patients (53 eyes) underwent DALK using "big bubble" technique due to keratoconus, corneal dystrophies and postinflammatory corneal opacification with continue Descemet's membrane and healthy endothelium. Best corrected visual acuity, main astigmatism, central corneal thickness, endothelium cell density, intra- and postoperative complications were assessed.
Mean follow up 15.4 months ranged from 11 to 24 months. Averaged best corrected visual acuity averaged equaled 0.6 and ranged from 0.1 to 4.0, mean astigmatism 2.6 D, ranged from 1.0 D to 2.6 D. Mean central corneal thickness was 503.4 microm and ranged from 379 microm to 694 microm, mean endothelium cell density before surgery equaled 2895/ mm2 and postoperatively 2398/ mm2. Incomplete Descemet's membrane detachment was diagnosed in 3 cases, intraoperative microperforations in 5 eyes and conversion to penetrating keratoplasty was needed in 4 patients. Postoperative disc opacity in 3 cases, increase of intraocular preassures in 1 case and early postoperative Descemet's membrane detachment in 1 eye. Posterior cataract formation in 4 eyes and in 1 case permanent mydriasis (Urrets-Zavalia Syndrome), was observed. There was no graft rejection observed.
Although technically more demanding lamellar keratoplasty, could be considered as an alternative "gold standard" penetrating keratoplasty.
介绍2006年至2008年在卡托维兹地区铁路医院眼科使用“大泡”技术进行的深前板层角膜移植术(DALK)的结果。
53例(53眼)因圆锥角膜、角膜营养不良和炎症后角膜混浊且后弹力层连续、内皮健康而接受了使用“大泡”技术的DALK。评估最佳矫正视力、主要散光、中央角膜厚度、内皮细胞密度、术中和术后并发症。
平均随访15.4个月,范围为11至24个月。平均最佳矫正视力平均为0.6,范围为0.1至4.0,平均散光2.6 D,范围为1.0 D至2.6 D。平均中央角膜厚度为503.4微米,范围为379微米至694微米,术前平均内皮细胞密度为2895/mm²,术后为2398/mm²。3例诊断为后弹力层不完全脱离,5眼术中出现微小穿孔,4例患者需要转为穿透性角膜移植术。术后3例出现植片混浊,1例眼压升高,1眼术后早期出现后弹力层脱离。观察到4眼发生后发性白内障,1例出现永久性瞳孔散大(乌雷茨-萨瓦利亚综合征)。未观察到移植排斥反应。
尽管板层角膜移植术技术要求更高,但可被视为穿透性角膜移植术的替代“金标准”。