Department of Cardiology, Toyohashi Heart Center, Toyohashi, Japan.
JACC Cardiovasc Interv. 2010 Feb;3(2):155-64. doi: 10.1016/j.jcin.2009.10.030.
The study evaluates the feasibility and efficacy of the novel modification of the retrograde recanalization of the chronic total occlusion (CTO) of the coronary arteries by using intravascular ultrasound (IVUS)-guided reverse controlled antegrade and retrograde tracking (CART).
Despite improvement in the techniques and materials, CTO recanalization is still suboptimal. The CART procedure has improved success rates, but there are certain inherent technical uncertainties and risk with this procedure.
This first series involves 31 patients, with 22 patients having previous failed attempts at CTO recanalization. All patients were treated with bilateral approach and using IVUS-guided reverse CART concept.
Successful recanalization of the CTO was achieved in all cases (100%). The access route was septal collateral in 20 (70%) cases and epicardial collateral in 11 (30%) cases. IVUS guidance was used successfully in 30 cases, and the channel dilator (microcatheter) was used in 27 cases. Guidewire injury and grade 1 perforation was seen in 3 (9%) cases, which were managed conservatively. There was no death, coronary artery bypass surgery, or pericardiocentesis in this group of patients. Mean fluoroscopy time was 65.84 +/- 23.16 min, ranging from 31 to 106 min and total contrast volume used 321.32 +/- 137.77 ml (range 115 to 650 ml).
This first series describes a high success rate of CTO recanalization with IVUS-guided reverse CART in selected patients performed by an experienced operator.
本研究评估了使用血管内超声(IVUS)引导下逆向控制顺行和逆行跟踪(CART)对冠状动脉慢性完全闭塞(CTO)进行新型逆行再通的可行性和疗效。
尽管技术和材料有所改进,但 CTO 再通率仍不理想。CART 手术提高了成功率,但该手术存在一定的固有技术不确定性和风险。
该系列首次涉及 31 例患者,其中 22 例患者之前曾尝试过 CTO 再通但失败。所有患者均采用双侧入路和 IVUS 引导下逆向 CART 概念进行治疗。
所有病例(100%)均成功实现 CTO 再通。20 例(70%)采用间隔侧支入路,11 例(30%)采用心外膜侧支入路。30 例成功使用 IVUS 引导,27 例使用通道扩张器(微导管)。3 例(9%)出现导丝损伤和 1 级穿孔,均予保守治疗。该组患者无死亡、冠状动脉旁路移植术或心包穿刺术。平均透视时间为 65.84 ± 23.16 分钟,范围为 31 至 106 分钟,总造影剂用量为 321.32 ± 137.77ml(范围为 115 至 650ml)。
本系列首次描述了在有经验的操作者进行的、选择合适患者的情况下,使用 IVUS 引导下逆向 CART 进行 CTO 再通的高成功率。