降钙素原在睾丸扭转与附睾炎-睾丸炎的鉴别诊断中有价值吗？

Is procalcitonin valuable in the differential diagnosis of testicular torsion and epididymo-orchitis.

作者信息

Yamis Sait, Gedik Abdullah, Sahin Hayrettin, Batun Sabri, Nergiz Yusuf, Bircan Kamuran

机构信息

Department of Urology, Medical School, Dicle University, Diyarbakir 21280, Turkey.

出版信息

Saudi Med J. 2010 Feb;31(2):170-4.

PMID:20174733

Abstract

OBJECTIVE

To evaluate the efficacy of procalcitonin (PCT) in the differential diagnosis of testicular torsion and epididymo-orchitis.

METHODS

This experimental study was performed in the research laboratory of Dicle University, School of Medicine, Diyarbakir, Turkey between March and June 2008. The study included 24 male rats randomized equally in 3 groups: sham, epididymo-orchitis, and torsion groups. Blood samples were obtained from all rats at the beginning of the study. After torsion and infection occurred in the testes, new blood samples were obtained for PCT measurement. Then, all the right testes of the rats were excised for histopathological evaluation. The Wilcoxon signed test was used for statistical evaluation.

RESULTS

Pre- and post PCT levels were statically compared, and PCT levels were significantly higher in the epididymo-orchitis group.

CONCLUSION

Procalcitonin could be an easy, fast, and safe marker for use in the differential diagnosis of testicular torsion and epididymo-orchitis.

摘要

目的

评估降钙素原（PCT）在睾丸扭转与附睾炎鉴别诊断中的效能。

方法

本实验研究于2008年3月至6月在土耳其迪亚巴克尔市迪克莱大学医学院的研究实验室进行。该研究纳入了24只雄性大鼠，平均随机分为3组：假手术组、附睾炎组和扭转组。在研究开始时从所有大鼠采集血样。在睾丸发生扭转和感染后，采集新的血样用于PCT检测。然后，切除所有大鼠的右侧睾丸进行组织病理学评估。采用Wilcoxon符号秩检验进行统计学评估。