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Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae.
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Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange.
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Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae.
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Mus81-Mms4 and Yen1 resolve a novel anaphase bridge formed by noncanonical Holliday junctions.
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Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.
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Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions.
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Flap endonuclease Rad27 cleaves the RNA of R-loop structures to suppress telomere recombination.
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Expression of MUS81 Mediates the Sensitivity of Castration-Resistant Prostate Cancer to Olaparib.
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Canonical and novel non-canonical activities of the Holliday junction resolvase Yen1.
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Implications of Metastable Nicks and Nicked Holliday Junctions in Processing Joint Molecules in Mitosis and Meiosis.
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Homologous recombination and Mus81 promote replication completion in response to replication fork blockage.
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Resolvases, Dissolvases, and Helicases in Homologous Recombination: Clearing the Road for Chromosome Segregation.
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Helicase/SUMO-targeted ubiquitin ligase Uls1 interacts with the Holliday junction resolvase Yen1.
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Structure-Specific Endonucleases and the Resolution of Chromosome Underreplication.
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Collaboration in the actions of Brh2 with resolving functions during DNA repair and replication stress in Ustilago maydis.
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The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant.
Nucleic Acids Res. 2010 Apr;38(6):1866-73. doi: 10.1093/nar/gkp1179. Epub 2009 Dec 29.
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Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.
Cell. 2009 Jul 10;138(1):78-89. doi: 10.1016/j.cell.2009.06.029.
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Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Cell. 2009 Jul 10;138(1):63-77. doi: 10.1016/j.cell.2009.06.030.
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Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.
Mol Cell. 2009 Jul 10;35(1):128-35. doi: 10.1016/j.molcel.2009.06.019.
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Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.
Mol Cell. 2009 Jul 10;35(1):116-27. doi: 10.1016/j.molcel.2009.06.020.
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Control of genome stability by SLX protein complexes.
Biochem Soc Trans. 2009 Jun;37(Pt 3):495-510. doi: 10.1042/BST0370495.
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Nucleases and helicases take center stage in homologous recombination.
Trends Biochem Sci. 2009 May;34(5):264-72. doi: 10.1016/j.tibs.2009.01.010. Epub 2009 Apr 15.
8
Identification of Holliday junction resolvases from humans and yeast.
Nature. 2008 Nov 20;456(7220):357-61. doi: 10.1038/nature07470.
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Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae.
Mol Cell. 2008 Sep 26;31(6):800-12. doi: 10.1016/j.molcel.2008.08.025.
10
Break-induced replication: what is it and what is it for?
Cell Cycle. 2008 Apr 1;7(7):859-64. doi: 10.4161/cc.7.7.5613. Epub 2008 Jan 14.
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