Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Curr Opin Urol. 2010 May;20(3):223-8. doi: 10.1097/MOU.0b013e32833817aa.
To assess the current status and technological advances in image-guided external beam radiotherapy for prostate cancer.
Modern imaging has improved the ability to define radiotherapy target volumes. Specifically, treatment margins have been reduced through the use of treatment planning and image-guidance technology. Increasing dose has led to increased disease control. Concurrent technological advances may improve treatment-related toxicity. Data continues to emerge on patient selection, treatment schedule, and use of additional systemic therapy in conjunction with radiation.
In the present article, we review recent developments in radiation planning, image guidance, patient selection and fractionation, dose escalation, toxicity, systemic therapy, and follow-up.
评估目前前列腺癌图像引导外照射放疗的现状和技术进展。
现代影像学提高了定义放疗靶区的能力。具体而言,通过使用治疗计划和图像引导技术,减少了治疗边缘。增加剂量可提高疾病控制率。同时的技术进步可能会改善与治疗相关的毒性。关于患者选择、治疗方案以及与放疗联合使用额外的系统治疗的数据不断涌现。
本文综述了放疗计划、图像引导、患者选择和分割、剂量递增、毒性、系统治疗以及随访方面的最新进展。