Grubb Mandy, Gaurav Kumar, Panda Mukta
Department of Medicine, University of Tennessee, College of Medicine, 960 East Third Street, Suite 208, Chattanooga, TN 37403, USA.
Cases J. 2009 Sep 16;2:8198. doi: 10.1186/1757-1626-0002-0000008198.
Most cases of hypercalcaemia are secondary to malignancy or primary hyperparathyroidism. Here we report a case of hypercalcaemia that we have attributed to milk-alkali syndrome.
A 51-year-old Caucasian woman with a past history of thyroidectomy and parathyroidectomy secondary to thyroid cancer developed an altered mental state and had an extremely high calcium concentration of 22.8 mg/dl (5.7 mmol/l). Investigations included work up for malignancy and hyperparathyroidism. However, the hypercalcaemia was attributed to ingestion of large doses of calcium carbonate, leading to milk-alkali syndrome. She was managed with intravenous fluids and withdrawal of calcium carbonate. The patient responded well to treatment, with normalization of the calcium concentration and clinical improvement.
We present this case to remind clinicians of the importance of detailed history taking and of milk-alkali syndrome as a cause of hypercalcemia.
大多数高钙血症病例继发于恶性肿瘤或原发性甲状旁腺功能亢进。在此,我们报告一例我们归因于乳-碱综合征的高钙血症病例。
一名51岁的白人女性,既往有因甲状腺癌行甲状腺切除术和甲状旁腺切除术的病史,出现精神状态改变,血钙浓度极高,达22.8mg/dl(5.7mmol/l)。检查包括对恶性肿瘤和甲状旁腺功能亢进的检查。然而,高钙血症归因于摄入大量碳酸钙,导致乳-碱综合征。她接受了静脉补液治疗,并停用了碳酸钙。患者对治疗反应良好,血钙浓度恢复正常,临床症状改善。
我们展示此病例是为提醒临床医生详细询问病史的重要性以及乳-碱综合征作为高钙血症病因的情况。