Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Cold Spring Harb Perspect Biol. 2010 Jan;2(1):a001594. doi: 10.1101/cshperspect.a001594.
There is abundant evidence of multiple biosynthesis pathways for the major naturally occurring auxin in plants, indole-3-acetic acid (IAA), and examples of differential use of two general routes of IAA synthesis, namely Trp-dependent and Trp-independent. Although none of these pathways has been completely defined, we now have examples of specific IAA biosynthetic pathways playing a role in developmental processes by way of localized IAA synthesis, causing us to rethink the interactions between IAA synthesis, transport, and signaling. Recent work also points to some IAA biosynthesis pathways being specific to families within the plant kingdom, whereas others appear to be more ubiquitous. An important advance within the past 5 years is our ability to monitor IAA biosynthesis and metabolism at increasingly higher resolution.
有大量证据表明，植物中主要天然生长素吲哚乙酸（IAA）存在多种生物合成途径，并且存在两种一般的 IAA 合成途径（色氨酸依赖型和非依赖型）的差异使用实例。尽管这些途径尚未完全定义，但我们现在已经有具体的 IAA 生物合成途径的例子，通过局部 IAA 合成在发育过程中发挥作用，这使我们重新思考 IAA 合成、运输和信号之间的相互作用。最近的工作还表明，一些 IAA 生物合成途径是植物王国特定家族特有的，而其他途径似乎更为普遍。在过去 5 年中，一个重要的进展是我们能够以越来越高的分辨率监测 IAA 的生物合成和代谢。
