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冷冻消融与射频消融治疗房室结折返性心动过速:6 毫米尖端导管冷冻消融的效果仍不如射频消融。

Cryoablation versus radiofrequency ablation for treatment of atrioventricular nodal reentrant tachycardia: cryoablation with 6-mm-tip catheters is still less effective than radiofrequency ablation.

机构信息

Heart Rhythm Service, St. Bartholomew's Hospital, London, UK.

出版信息

Heart Rhythm. 2010 Mar;7(3):340-3. doi: 10.1016/j.hrthm.2009.11.029. Epub 2009 Dec 2.

Abstract

BACKGROUND

The treatment of choice for atrioventricular nodal reentrant tachycardia (AVNRT) is catheter ablation of the atrioventricular nodal slow pathway.

OBJECTIVE

The purpose of this study was to ascertain whether cryoablation (Cryo) with 6-mm-tip catheters is as effective as radiofrequency ablation (RF).

METHODS

Patients who had catheter ablation for AVNRT between 2005 and 2008 were identified. The main outcome measure was overall success without the use of an alternative energy source and no recurrence.

RESULTS

Two hundred eighty-eight procedures in 272 patients were identified; 184 were female (68%), and the mean age was 53 +/- 14 (17-88) years. There were 123 Cryo and 149 RF procedures. Cryo had a lower overall success rate (83% vs. 93%; P = .02). Mean procedure times were similar in both groups (90 minutes; P = .5). Fluoroscopy time was longer with Cryo: 16 (7-48) versus 14 (5-50) minutes (P = .04). Only one case of atrioventricular block was observed in the RF group (0.7%). Cryo was more expensive than RF ( pounds sterling 3141 vs. pounds sterling 2153).

CONCLUSION

Even when delivering multiple lesions with 6-mm-tip catheters, Cryo is less effective than RF. RF is recommended as a first-line treatment, although the only major complication occurred in the RF group.

摘要

背景

房室结折返性心动过速(AVNRT)的治疗选择是房室结慢径消融。

目的

本研究旨在确定 6 毫米尖端导管冷冻消融(Cryo)是否与射频消融(RF)一样有效。

方法

确定了 2005 年至 2008 年间接受 AVNRT 导管消融的患者。主要观察指标是无替代能源使用和无复发的整体成功率。

结果

确定了 272 例患者中的 288 例手术;184 例为女性(68%),平均年龄为 53+/-14 岁(17-88 岁)。有 123 例 Cryo 和 149 例 RF 手术。Cryo 的整体成功率较低(83%对 93%;P=0.02)。两组的平均手术时间相似(90 分钟;P=0.5)。Cryo 的透视时间较长:16(7-48)对 14(5-50)分钟(P=0.04)。RF 组仅观察到 1 例房室传导阻滞(0.7%)。Cryo 比 RF 更昂贵(英镑 3141 对 2153 英镑)。

结论

即使使用 6 毫米尖端导管进行多次消融,Cryo 的效果也不如 RF。RF 被推荐为一线治疗方法,尽管唯一的主要并发症发生在 RF 组。

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