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[通过体容积描记法测量儿童在封堵器闭合与未闭合时气道阻力的差异]

[Differences in airway resistances in children measured by plethysmography with and without closure of the occluder].

作者信息

Sardón Olaia, Pérez-Yarza Eduardo G, Aldasoro Ane, Korta Javier, Corcuera Paula, Mintegui Javier, Emparanza Jose Ignacio

机构信息

Sección de Neumología Infantil, Servicio de Pediatría, Osakidetza, Hospital Donostia, San Sebastián, Spain.

出版信息

Arch Bronconeumol. 2010 Apr;46(4):160-4. doi: 10.1016/j.arbres.2010.01.001. Epub 2010 Feb 24.

Abstract

BACKGROUND

There have been several studies that have measured airway resistances using plethysmography without closing the occluder.

OBJECTIVE

To investigate the differences between the total resistances (sRaw(TOT)) and the specific resistances (sRaw) with the same technique (plethysmography) but different methodology (with and without closure of the occluder) in child subjects.

MATERIAL AND METHODS

An observational and cross-sectional study of a consecutive sample of children between 6 and 14 years old who were seen at the Childhood Pneumology clinics from 15th January to 15th February 2009. Determination of sRaw(TOT), sRaw and specific conductance (sGaw) using plethysmography (MasterLab V5.1, Viasys, Wuerzburg, Germany) without closing the occluder. The same determinations were then performed with the occluder closed. The qualitative variables were: sex, diagnosis and treatment, and the quantitative variables: age, weight, height, sRaw(TOT), sRaw, sGaw and respiratory rate with and without closing the occluder. The results were analysed for association and concordance between sRaw(TOT), sRaw and sGaw with and without closure of the occluder using paired Student t test, Bland-Altman method and a scatter plot.

RESULTS

Thirty-six cases were included and all (100%) the tests were performed successfully. The mean age was 9.91+/-2.37 years. There were no differences between sRawTOT, sRaw or sGaw with and without closure of the occluder. Neither were there any differences between the regression of the means obtained for sRaw(TOT), sRaw and sGaw with and without closure of the occluder.

CONCLUSIONS

There is good agreement between the sRaw(TOT) y sRaw obtained by plethysmography with and without closure of the occluder.

摘要

背景

已有多项研究使用体容积描记法在不关闭阻塞器的情况下测量气道阻力。

目的

探讨在儿童受试者中,采用相同技术(体容积描记法)但不同方法(阻塞器关闭和不关闭)时总阻力(sRaw(TOT))和比阻力(sRaw)之间的差异。

材料与方法

对2009年1月15日至2月15日在儿童肺病门诊就诊的6至14岁儿童连续样本进行观察性横断面研究。使用体容积描记法(MasterLab V5.1,Viasys,德国维尔茨堡)在不关闭阻塞器的情况下测定sRaw(TOT)、sRaw和比传导率(sGaw)。然后在阻塞器关闭的情况下进行相同的测定。定性变量为:性别、诊断和治疗,定量变量为:年龄、体重、身高、阻塞器关闭和不关闭时的sRaw(TOT)、sRaw、sGaw和呼吸频率。使用配对学生t检验、布兰德-奥特曼方法和散点图分析阻塞器关闭和不关闭时sRaw(TOT)、sRaw和sGaw之间的关联和一致性。

结果

纳入36例病例,所有(100%)测试均成功完成。平均年龄为9.91±2.37岁。阻塞器关闭和不关闭时,sRawTOT、sRaw或sGaw之间无差异。阻塞器关闭和不关闭时,sRaw(TOT)、sRaw和sGaw所得均值的回归之间也无差异。

结论

体容积描记法在阻塞器关闭和不关闭时获得的sRaw(TOT)和sRaw之间具有良好的一致性。

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