吉非替尼与出血性膀胱炎和严重挛缩膀胱的关联：一例报告。
Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report.
机构信息
Department of Urology, Aichi Medical University School of Medicine, Nagakute, Aichi 480-1195, Japan.
出版信息
BMC Urol. 2010 Feb 26;10:6. doi: 10.1186/1471-2490-10-6.
BACKGROUND
Gefitinib remains an excellent treatment option for patients with a variety of cancers, including non small cell lung cancer (NSCLC). However, clinicians must be aware of the potential of gefitinib to cause an inflammatory reaction in the skin, lungs and bladder.
CASE PRESENTATION
We present a case on hemorrhagic cystitis and severely contracted bladder in a patient with NSCLC on gefitinib.
CONCLUSIONS
Further studies are needed to substantiate the association of gefitinib therapy with hemorrhagic cystitis and contracted bladder.
背景
吉非替尼仍然是包括非小细胞肺癌（NSCLC）在内的多种癌症患者的极佳治疗选择。然而，临床医生必须意识到吉非替尼可能会引起皮肤、肺部和膀胱的炎症反应。
病例介绍
我们报告了一例 NSCLC 患者使用吉非替尼后出现出血性膀胱炎和严重膀胱挛缩的病例。
结论
需要进一步的研究来证实吉非替尼治疗与出血性膀胱炎和膀胱挛缩之间的关联。
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