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肌肉瓣在挽救感染性内固定外露植入物中的应用。

The use of muscle flaps in the salvage of infected exposed implants for internal fixation.

作者信息

Tan K-J, Lim C-T, Lim A Y-T

机构信息

University Orthopaedics, Hand and Reconstructive Microsurgery Cluster, National University Hospital, Young Loo Lin School of Medicine, National University of Singapore, National University Health System, 5 Lower Kent Ridge Road, Singapore.

出版信息

J Bone Joint Surg Br. 2010 Mar;92(3):401-5. doi: 10.1302/0301-620X.92B3.22115.

Abstract

The treatment of infected exposed implants which have been used for internal fixation usually involves debridement and removal of the implant. This can result in an unstable fracture or spinal column. Muscle flaps may be used to salvage these implants since they provide soft-tissue cover and fresh vascularity. However, there have been few reports concerning their use and these have concentrated on the eradication of the infection and successful soft-tissue cover as the endpoint. There is no information on the factors which may influence the successful salvage of the implant using muscle flaps. We studied the results and factors affecting outcome in nine pedicled muscle flaps used in the treatment of exposed metal internal fixation with salvage of the implant as the primary endpoint. This was achieved in four cases. Factors predicting success were age < 30 years, the absence of comorbid conditions and a favourable microbiological profile. The growth of multiple organisms, a history of smoking and the presence of methicillin-resistant Staphylococcus aureus on wound cultures indicated a poor outcome. The use of antibiotic beads, vacuum-assisted closure and dressing, the surgical site, the type of flap performed and the time from primary surgery to flap cover were not predictive of outcome.

摘要

对于已用于内固定的感染外露植入物的治疗通常包括清创和取出植入物。这可能导致骨折或脊柱不稳定。肌瓣可用于挽救这些植入物,因为它们能提供软组织覆盖和新的血运。然而,关于其使用的报道很少,且这些报道都以根除感染和成功的软组织覆盖作为终点。目前尚无关于可能影响使用肌瓣成功挽救植入物的因素的信息。我们以挽救植入物作为主要终点,研究了9个带蒂肌瓣用于治疗外露金属内固定的结果及影响预后的因素。4例实现了这一目标。预测成功的因素包括年龄<30岁、无合并症以及良好的微生物学特征。伤口培养中多种微生物生长、吸烟史以及耐甲氧西林金黄色葡萄球菌的存在表明预后不良。抗生素珠、负压封闭引流和敷料的使用、手术部位、所施行的肌瓣类型以及初次手术至肌瓣覆盖的时间均不能预测预后。

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