INSERM, CIC-EC CIE6, Centre Hospitalier Universitaire Nancy, Epidémiologie et Evaluation Cliniques, Nancy-University, Nancy, France.
Arthritis Care Res (Hoboken). 2010 Jan 15;62(1):54-62. doi: 10.1002/acr.20014.
To compare quality of life (QOL) scores 3 and 10 years after total hip arthroplasty (THA) or total knee arthroplasty (TKA) for osteoarthritis with QOL scores in a general population, and to determine factors associated with QOL after surgery.
Data were obtained from 2 multicenter cohorts of patients with THA or TKA: 232 patients were recruited during 2003 (3-year cohort) and 221 patients were recruited during 1994 (10-year cohort). Preoperative data (QOL, radiograph results) and followup data (demographics, comorbidities, pain locations, environmental factors, and QOL) were collected. QOL data for the general population were obtained from a 2003 population-based survey.
A total of 195 and 89 patients for the 3- and 10-year cohorts, respectively, were followed up; the mean age at followup was 73 years. For both of the cohorts, physical functioning and role-physical or role-emotional QOL scores were lower than those for a general population with comparable age. Scores for pain, mental health, and social dimensions were lower than those for the reference population for only the 10-year cohort. For both cohorts, increased number of comorbidities, painful locations other than THA or TKA location, and unfavorable environmental factors were associated with impaired QOL. Low preoperative QOL scores were predictive of impaired QOL at followup for only the 3-year cohort.
THA or TKA can improve QOL, but the benefits may be time limited. Addressing environmental factors and treating comorbidities and pain in locations other than the arthroplasty location could have mid- and long-term effects on the QOL of patients with THA or TKA.
比较全髋关节置换术(THA)或全膝关节置换术(TKA)治疗骨关节炎患者术后 3 年和 10 年的生活质量(QOL)评分与普通人群 QOL 评分,并确定与术后 QOL 相关的因素。
数据来自 2 个接受 THA 或 TKA 的多中心队列患者:2003 年招募了 232 例患者(3 年队列),1994 年招募了 221 例患者(10 年队列)。收集了术前数据(QOL、影像学结果)和随访数据(人口统计学、合并症、疼痛部位、环境因素和 QOL)。普通人群的 QOL 数据来自 2003 年的一项基于人群的调查。
3 年和 10 年队列分别有 195 例和 89 例患者随访,随访时的平均年龄为 73 岁。对于两个队列,身体功能以及身体角色或情绪角色 QOL 评分均低于年龄相当的普通人群。仅在 10 年队列中,疼痛、心理健康和社会维度的评分才低于参考人群。对于两个队列,合并症数量增加、THA 或 TKA 部位以外的疼痛部位以及不利的环境因素与 QOL 受损相关。仅在 3 年队列中,术前 QOL 评分较低与随访时 QOL 受损相关。
THA 或 TKA 可改善 QOL,但益处可能是有限的。解决环境因素以及治疗除置换部位以外的合并症和疼痛可能对 THA 或 TKA 患者的 QOL 产生中长期影响。