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[脊髓损伤治疗的现状与进展]

[Current situation and progression in the treatment of spinal cord injury].

作者信息

Li Sheng-hua, Guo Ping-de, Wang Wen-jing

机构信息

Traditional Chinese Medical Hospital of Gansu Province, Lanzhou 730050, Gansu, China.

出版信息

Zhongguo Gu Shang. 2010 Jan;23(1):70-3.

Abstract

Spinal cord injuries include original injury and secondary injury. The aim of therapy is to prevent and reduce the secondary injury. The traditional therapy can alleviate the secondary injury of spinal cord through surgery that can both relieve the pressure of spinal cord and maintain the spinal stability with the internal fixation, medicine and hyperbaric oxygen therapy were applied together. But, the effect of neuroprotection and neurotization of traditional therapy is worse and the most of all is the environment in the spinal cord injury that make against the repairing. At present, the treatment of spinal cord injury with cell transplantation and gene therapy have made achievements in the animal experiment and have been simply tested in clinical. Cell transplantation and gene therapy have a great clinical utilization.

摘要

脊髓损伤包括原发性损伤和继发性损伤。治疗的目的是预防和减少继发性损伤。传统疗法可通过手术减轻脊髓继发性损伤,手术既能解除脊髓压迫,又能通过内固定维持脊柱稳定性,同时应用药物和高压氧治疗。但是,传统疗法的神经保护和神经再生效果较差,最重要的是脊髓损伤的环境不利于修复。目前,细胞移植和基因治疗在脊髓损伤治疗方面在动物实验中已取得成果,并已在临床进行了初步试验。细胞移植和基因治疗具有很大的临床应用价值。

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