[北京农村社区颅内及颅外大动脉狭窄的发病率和预后]

[Incidence and prognosis of intra-and extracranial large-artery stenosis in the rural community of Beijing].

作者信息

Xing Hai-Ying, Gao Hui-Zhen, Tan Xiu-Ge, Fan Chang-Feng, Gao Shan, Sun Yong-An, Zhang Hua, Zhong Xian-Hua, Liu Hui-Jun, Huang Yi-Ning

机构信息

Department of Neurology, First Hospital of Peking University, Beijing 100034, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Aug;30(8):780-3.

PMID:20193197

Abstract

OBJECTIVE

To assess the prevalence rates of intra- and extracranial large-artery stenosis in the rural community population and its related risk to the development of stroke.

METHODS

The study subjects included 1337 residents in the rural community of Beijing. Transcranial Doppler was carried our to examine the relation between intra- and extracranial large-artery stenosis and subsequent cerebrovascular events, with a mean follow-up period of 16.7 months.

RESULTS

The incidence densities of cerebral infarction and cerebral hemorrhage in persons without cerebral large-artery stenosis were 410.6 and 351.9/100-thousand person-years, respectively. In the group with large-artery stenosis, the incidence density of cerebral infarction was 3303.7/100-thousand person-years. Data from The Fisher's Exact test showed a significant difference in the two groups (P = 0.004). Cerebral large-artery stenosis (OR = 6.593, 95%CI: 1.712 - 25.390) and smoking (OR = 8.437, 95%CI: 2.327 - 30.598) appeared to be independent risk factors to cerebral infarction.

CONCLUSION

Cerebral large-artery stenosis and smoking were independent risk factors to cerebral infarction.

摘要

目的

评估农村社区人群颅内和颅外大动脉狭窄的患病率及其与中风发生的相关风险。

方法

研究对象包括北京农村社区的1337名居民。采用经颅多普勒检查颅内和颅外大动脉狭窄与随后脑血管事件之间的关系，平均随访期为16.7个月。

结果

无脑大动脉狭窄者脑梗死和脑出血的发病密度分别为410.6和351.9/10万人口年。在大动脉狭窄组中，脑梗死的发病密度为3303.7/10万人口年。Fisher精确检验数据显示两组有显著差异（P = 0.004）。脑大动脉狭窄（OR = 6.593，95%CI：1.712 - 25.390）和吸烟（OR = 8.437，95%CI：2.327 - 30.598）似乎是脑梗死的独立危险因素。