Skinner Joline E, Driscoll Sherilyn W, Porter Co-Burn J, Brands Chad K, Pianosi Paolo T, Kuntz Nancy L, Nelson Dawn E, Burkhardt Barbara E, Bryant Sandra C, Fischer Philip R
Mayo Clinic College of Medicine, Department of Physical Medicine and Rehabilitation, Rochester, Minnesota 55905, USA.
J Child Neurol. 2010 Oct;25(10):1210-5. doi: 10.1177/0883073809359539. Epub 2010 Mar 1.
This descriptive population study of 307 public high school students, ages 15 to 17 years, was performed to establish reference ranges for orthostatic changes in heart rate and blood pressure in adolescents, and to identify influential variables. Noninvasive measurements of blood pressure and heart rate were obtained. Reference ranges for orthostatic heart rate change in this population at 2 minutes were -2 to +41 beats per minute and at 5 minutes were -1 to +48 beats per minute. Orthostatic blood pressure changes were within the adult range for 98% of adolescents tested. One-third of participants experienced orthostatic symptoms during testing. In conclusion, this study shows that orthostatic symptoms and large orthostatic heart rate changes occur in adolescents. This suggests that the current orthostatic heart rate criterion aiding the diagnosis of adult orthostatic intolerance syndromes is likely not appropriate for adolescents and should be reevaluated.
这项针对307名年龄在15至17岁的公立高中生的描述性人群研究，旨在确定青少年直立位心率和血压变化的参考范围，并识别有影响的变量。获取了血压和心率的无创测量值。该人群在2分钟时直立位心率变化的参考范围是每分钟-2至+41次心跳，在5分钟时是每分钟-1至+48次心跳。98%接受测试的青少年直立位血压变化在成人范围内。三分之一的参与者在测试过程中出现直立位症状。总之，这项研究表明青少年会出现直立位症状和较大的直立位心率变化。这表明当前辅助诊断成人直立性不耐受综合征的直立位心率标准可能不适用于青少年，应重新评估。
