Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea.
NeuroRehabilitation. 2010;26(2):173-6. doi: 10.3233/NRE-2010-0551.
The object of this study was to demonstrate the reorganization of the affected hand motor function lateral to the congenital brain lesion in a patient using functional MRI (fMRI).
Twelve normal control subjects and a 23-year-old man with a congenital brain lesion including the precentral knob were evaluated. FMRI was performed using the blood oxygen level-dependent technique at 1.5-T system with timed hand grasp-lease motor tasks.
The contralateral primary sensorimotor cortex centered on the precentral knob was activated during hand movements of the right side of the patient and of control subjects. However, only the lateral area of the lesion was activated during left hand movements of the patient.
It seems that the motor function of the left hand was reorganized into the lateral area of the lesion in this patient. This finding may reflect a cortical reorganization of the motor area.
本研究旨在利用功能磁共振成像（fMRI）显示一位患者患侧手运动功能在先天性脑损伤部位的重组。
评估了 12 名正常对照者和一名 23 岁患有包括中央前回隆凸在内的先天性脑损伤的男性。使用 1.5-T 系统和计时手抓-释放运动任务，通过血氧水平依赖技术进行 fMRI。
在患者右侧和对照组的手部运动过程中，对侧初级感觉运动皮层集中在中央前回隆凸。然而，在患者的左手运动过程中，只有损伤的外侧区域被激活。
在这位患者中，左手的运动功能似乎已经重组到病变的外侧区域。这一发现可能反映了运动区的皮质重组。
