Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard University, 330 Brookline Avenue, Boston, MA 02215, USA.
Matern Child Health J. 2011 Apr;15(3):352-9. doi: 10.1007/s10995-010-0587-6.
Folic acid use started prior to pregnancy confers a decreased risk of neural tube defects, and yet 20-50% of pregnancies are unplanned. We sought to determine whether medical providers order folic acid (FA) or folic acid-containing multivitamins (MVI) for their non-pregnant female patients of childbearing age. This is a cross-sectional study using data from the CDC's National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS) (2005 and 2006). Among non-pregnant, female patients of childbearing age (15-44), the proportion of preventive visits during which a provider ordered FA/MVI supplements was determined and compared to pregnant patients. Next, the rates of FA/MVI orders were examined according to race/ethnicity, age, insurance status, region of the country, provider type, contraceptive care, income and education. Analyses were conducted using SAS-callable Sudaan to account for survey design and to obtain population estimates. There were 4,634 preventive visits for non-pregnant women of childbearing age, representing 32.1 million visits nationally. Of these visits, 7.2% included provider-ordered FA/MVI. Multivariable logistic regression analyses revealed that provider-ordered FA/MVI was most common for women ages 30-34, who receive Medicaid, and whose race/ethnicity was other than White, Black or Hispanic. Preventive care visits represent an important venue for counseling regarding the benefits of FA for women of childbearing age, but appear to be under-utilized in all women. Our findings suggest that annually there may be over 29 million missed opportunities to recommend folic acid to non-pregnant women seeking preventive care.
叶酸在怀孕前使用可以降低神经管缺陷的风险,但仍有 20-50%的妊娠是意外的。我们试图确定医疗保健提供者是否为其处于生育年龄的非怀孕女性患者开叶酸(FA)或含叶酸的多种维生素(MVI)。这是一项使用疾病预防控制中心国家门诊医疗保健调查(NAMCS)和国家医院门诊医疗保健调查(NHAMCS)(2005 年和 2006 年)数据的横断面研究。在非怀孕的生育年龄女性患者(15-44 岁)中,确定了提供者在预防就诊时开 FA/MVI 补充剂的比例,并与怀孕患者进行了比较。接下来,根据种族/族裔、年龄、保险状况、国家地区、提供者类型、避孕护理、收入和教育,检查了 FA/MVI 订单的比率。使用 SAS 可调用的 Sudaan 进行分析,以考虑到调查设计并获得人口估计数。共有 4634 次非怀孕生育年龄女性的预防就诊,代表全国 3210 万次就诊。在这些就诊中,有 7.2%的就诊包括提供者开的 FA/MVI。多变量逻辑回归分析显示,最常开 FA/MVI 的是年龄在 30-34 岁之间的女性,她们接受医疗补助,种族/族裔不是白人、黑人或西班牙裔。预防保健就诊是为生育年龄女性提供叶酸益处咨询的重要场所,但在所有女性中似乎都未得到充分利用。我们的研究结果表明,每年可能有超过 2900 万次错过向寻求预防保健的非怀孕女性推荐叶酸的机会。