Laturnus J M, Gebhard M, Sommerauer M, Jocham D, Doehn C
Klinik und Poliklinik für Urologie, Universitätsklinikum Schleswig-Holstein (UKSH), Campus Lübeck.
Aktuelle Urol. 2010 May;41(3):197-9. doi: 10.1055/s-0029-1224735. Epub 2010 Mar 4.
A prostatic stromal tumour of uncertain malignant potential (STUMP) is a non-epithelial, mesenchymal spindle-cell tumour that can be classified as a specialised stromal tumour of the prostate. Although in most cases STUMP is not of an aggressive nature, occasional cases have been documented with an extension into adjacent tissues or recurrence after resection. A minority of cases develop a sarcomatous dedifferentiation.We report the case of a 53-year-old male with symptoms of febrile prostatitis. After consolidation we performed TUR-P due to urinary retention. Finally, we made the pathological diagnosis of prostatic STUMP. The patient is being seen -frequently in our clinic to take prostate biopsies to exclude a progression into a stromal sarcoma (active surveillance). After 13 months the STUMP is still detectable, but with no signs of sarcoma.
具有不确定恶性潜能的前列腺基质肿瘤(STUMP)是一种非上皮性间充质梭形细胞瘤,可归类为前列腺的特殊基质肿瘤。虽然大多数情况下STUMP并非侵袭性肿瘤,但偶尔也有病例记录显示其可侵犯邻近组织或切除后复发。少数病例会发生肉瘤样去分化。我们报告一例53岁男性,有发热性前列腺炎症状。在病情稳定后,因尿潴留行经尿道前列腺切除术(TUR-P)。最终,我们做出了前列腺STUMP的病理诊断。该患者在我们诊所定期接受前列腺活检,以排除进展为基质肉瘤(主动监测)。13个月后,仍可检测到STUMP,但无肉瘤迹象。