Division of Vascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
J Vasc Surg. 2010 Mar;51(3):634-8. doi: 10.1016/j.jvs.2009.11.061.
This study used air plethysmographic parameters to evaluate the changes in venous hemodynamics after the surgical treatment of primary varicose veins.
We retrospectively analyzed 1756 limbs of 1620 patients who had undergone surgery for great saphenous vein (GSV) reflux from January 1996 to June 2009 at Samsung Medical Center. Venous hemodynamic changes were evaluated by performing air plethysmography preoperatively and 1 month postoperatively and assessing the venous volume (VV), the venous filling index (VFI), the residual volume fraction (RVF), and the ejection fraction (EF).
Preoperatively, median (interquartile range) values were VV, 121.6 (94.7-160.6) mL; VFI, 4.8 (2.9-7.6) mL/s; RVF, 40.6% (29.7%-50.0%); and EF, 53.5% (44.3%-64.1%). Postoperatively, the median (interquartile range) values were VV, 90.6 (69.1-116.8) mL; VFI, 1.4 (0.9-1.9) mL/s; RVF, 28.4% (17.5%-38.7%); and EF, 65.2% (54.5%-77.2%). VV, VFI, and RVF were reduced 25.2%, 71.5%, and 29.9%, respectively; EF was increased 20.3%. The results were significant for all four variables (P < .001). We compared the degree of hemodynamic changes according to the treatment modalities: the high ligation and stripping group , 1578 cases; the GSV valvuloplasty group, 124 cases; and the VNUS group (VNUS Medical Technologies Inc, San Jose, CA), 54 cases. The reduction of the VV, VFI, and RVF was greater in the GSV stripping group and in the VNUS group than in the valvuloplasty group (P < .001), yet no difference was noted in the EF increase among the surgical modalities (P = .157).
Our results show that the venous hemodynamic parameters of primary varicose veins were improved after surgical treatment.
本研究使用空气体积描记法参数评估原发性静脉曲张手术后静脉血液动力学的变化。
我们回顾性分析了 1996 年 1 月至 2009 年 6 月在三星医疗中心接受大隐静脉(GSV)反流手术的 1620 例患者的 1756 条肢体。通过术前和术后 1 个月进行空气体积描记法评估静脉血液动力学变化,并评估静脉容量(VV)、静脉充盈指数(VFI)、残余容积分数(RVF)和射血分数(EF)。
术前,中位数(四分位间距)值为 VV,121.6(94.7-160.6)ml;VFI,4.8(2.9-7.6)ml/s;RVF,40.6%(29.7%-50.0%);EF,53.5%(44.3%-64.1%)。术后,中位数(四分位间距)值为 VV,90.6(69.1-116.8)ml;VFI,1.4(0.9-1.9)ml/s;RVF,28.4%(17.5%-38.7%);EF,65.2%(54.5%-77.2%)。VV、VFI 和 RVF 分别减少 25.2%、71.5%和 29.9%;EF 增加 20.3%。所有四个变量的结果均具有统计学意义(P<.001)。我们根据治疗方式比较了血液动力学变化的程度:高位结扎和剥脱组 1578 例;GSV 瓣膜成形术组 124 例;VNUS 组(VNUS Medical Technologies Inc,加利福尼亚州圣何塞)54 例。在 GSV 剥脱组和 VNUS 组中,VV、VFI 和 RVF 的减少程度大于瓣膜成形术组(P<.001),但手术方式之间 EF 增加无差异(P=0.157)。
我们的结果表明,原发性静脉曲张手术后静脉血液动力学参数得到了改善。