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对沙眼衣原体进行尿液检测以及提供轻松便捷的后续跟进服务,街头青少年对此表示接受。

Urine testing for Chlamydia trachomatis and hassle-free follow-up is acceptable to street youth.

作者信息

McCarthy A E, Macdonald N E, Feder S, Doherty J A, McAvoy L, Toye B

机构信息

Division of Infectious Diseases and.

出版信息

Paediatr Child Health. 1999 Sep;4(6):395-9. doi: 10.1093/pch/4.6.395.

Abstract

OBJECTIVE

To evaluate whether street youth would use a sexually transmitted disease (STD) screening program involving non-nominal, noninvasive testing of urine for Chlamydia trachomatis with hassle-free follow-up and partner self-notification.

DESIGN

Cross-sectional pilot study in six centres frequented by street youth 13 to 25 years of age in the Regional Municipality of Ottawa-Carleton.

INTERVENTIONS

A structured, non-nominal face-to-face interview using an 88-item questionnaire was administered by a trained research assistant. Immediate feedback was provided to participants about specific individual risk reduction strategies for high risk life styles. Each street youth provided a urine sample that was tested non-nominally for C trachomatis by polymerase chain reaction (PCR). A single dose of azithromycin therapy was provided to participants who tested positive, each of whom was requested to encourage recent sexual partners to come forward for testing and treatment.

RESULTS

One hundred and sixty-three street youth were recruited (98 males and 65 females [male to female ratio 1.5:1]) over the four months of the study. The mean ages of participants were males 18.3+/-2.50 years and females 16.7+/-2.02 years. Ninety-two per cent (146) of all participants were sexually active and 99% of the sexually active youth (145 of 146) submitted urine samples. Urine samples were positive in 12 (8.2%) participants (seven males, five females), all of whom were asymptomatic. All those who tested positive were recruited from a single site (site specific rate 13.6%). Overall, only 25% of those tested returned spontaneously for test results; however, nine of 12 participants with positive results were treated due to investigator vigilance in locating the youth. Street youth partner self-notification resulted in five additional street youth requesting testing and treatment.

CONCLUSIONS

Street youth participated in a STD testing program when a street friendly program and noninvasive methods were used. Although more expensive, urine PCR testing increased program acceptance by street youth compared with previous local results. Detection of C trachomatis was high in this hard-to-reach population. There is a need to address further the problem of poor return rates for results and treatment, as well as low rates of partner notification.

摘要

目的

评估街头青少年是否会使用一项性传播疾病(STD)筛查项目,该项目包括对尿液进行沙眼衣原体的非记名、非侵入性检测,并提供便捷的后续跟进及性伴侣自我通知服务。

设计

在渥太华-卡尔顿地区市政当局中,针对13至25岁街头青少年常去的六个中心开展横断面试点研究。

干预措施

由一名经过培训的研究助理使用一份包含88个条目的问卷进行结构化、非记名的面对面访谈。向参与者提供关于针对高风险生活方式的具体个人风险降低策略的即时反馈。每位街头青少年提供一份尿液样本,通过聚合酶链反应(PCR)对其进行非记名的沙眼衣原体检测。对检测呈阳性的参与者提供单剂量阿奇霉素治疗,并要求他们鼓励近期的性伴侣前来接受检测和治疗。

结果

在研究的四个月期间,招募了163名街头青少年(98名男性和65名女性[男女比例为1.5:1])。参与者的平均年龄男性为18.3±2.50岁,女性为16.7±2.02岁。所有参与者中有92%(146名)有性行为,99%有性行为的青少年(146名中的145名)提交了尿液样本。12名(8.2%)参与者的尿液样本呈阳性(7名男性,5名女性),他们均无症状。所有检测呈阳性的参与者均来自单个地点(该地点的特定感染率为13.6%)。总体而言,只有25%接受检测的人主动回来获取检测结果;然而,由于研究人员积极寻找这些青少年,12名检测结果呈阳性的参与者中有9名得到了治疗。街头青少年的性伴侣自我通知又使得另外5名街头青少年前来要求检测和治疗。

结论

当采用对街头友好的项目和非侵入性方法时,街头青少年会参与STD检测项目。尽管尿液PCR检测成本更高,但与之前当地的结果相比,它提高了街头青少年对该项目的接受度。在这个难以接触到的人群中,沙眼衣原体的检出率很高。需要进一步解决检测结果和治疗的回访率低以及性伴侣通知率低的问题。

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