Fall-Malick F Z, Bara A O, Lam M, Mint Beibacar M, Ba K, Ba H, Ould Ghady I, Ould Horma A, Toure-Kane N C, Mboup S, Lo B
Laboratoire de virologie, institut national de recherches en santé publique, BP 695, Nouakchott, Mauritanie.
Bull Soc Pathol Exot. 2010 Oct;103(4):243-5. doi: 10.1007/s13149-010-0042-3. Epub 2010 Mar 6.
According to the 2008 report on global AIDS epidemic, 33 millions of people are living with HIV/AIDS. Subsaharian Africa is the most affected part of the world. The first case of AIDS in Mauritania was reported in 1987. The national prevalence of HIV/AIDS in the country is estimated at less than 1%. The HIV serosurveillance among pregnant women started in country in 2001. This work has focused on HIV sentinel surveillance among pregnant women in antenatal clinics, attending health centres in different wilayas (regions) of the country in order to assess evolution of prevalence between 2001 and 2007. An anonymous and non-correlated method is used for this survey. A questionnaire was administered and venous sampling made for eligible women. Analyses were performed with an algorithm based on two screening tests (ELISA) and another test for confirmation (New Lav Blot). Despite some disparities between the sites considered, the results have shown a low prevalence rate (between 0.1 and 1.48). The average prevalence of HIV infection samples collected increased from 0.57% [0.34-0.80] in 2001 to 0.61% [0.40-0.82] in 2007 with 95% confidence interval. Statistical analysis showed no significant changes between 2001 and 2007 at all these sites. HIV1 is the most frequent type with a proportion of 93.5% in 2007. After several years of classic HIV sentinel surveillance, and to better understand disparities between sites, we recommend a second generation sentinel surveillance (behavioural and serological) approach.
根据2008年全球艾滋病疫情报告,有3300万人感染了艾滋病毒/艾滋病。撒哈拉以南非洲是世界上受影响最严重的地区。毛里塔尼亚于1987年报告了首例艾滋病病例。该国艾滋病毒/艾滋病的全国流行率估计低于1%。该国于2001年开始对孕妇进行艾滋病毒血清监测。这项工作重点关注该国不同省(地区)的产前诊所中孕妇的艾滋病毒哨点监测,以评估2001年至2007年期间流行率的变化。本次调查采用匿名且不相关联的方法。对符合条件的妇女发放问卷并采集静脉血样。分析采用基于两种筛查检测(酶联免疫吸附测定法)和另一种确认检测(新型免疫印迹法)的算法进行。尽管所考虑的各地点之间存在一些差异,但结果显示流行率较低(在0.1%至1.48%之间)。采集的艾滋病毒感染样本的平均流行率从2001年的0.57%[0.34 - 0.80]上升至2007年的0.61%[0.40 - 0.82],置信区间为95%。统计分析表明,在所有这些地点,2001年至2007年期间没有显著变化。艾滋病毒1型是最常见的类型,2007年占比93.5%。在进行了数年的经典艾滋病毒哨点监测之后,为了更好地了解各地点之间的差异,我们建议采用第二代哨点监测(行为学和血清学)方法。