伊朗健康成年人的血清叶酸和维生素 B12 状况。

Serum folate and vitamin B12 status in healthy Iranian adults.

机构信息

Endocrine and Metabolism Research Centre, Namazi Hospital, Shiraz, Islamic Republic of Iran.

出版信息

East Mediterr Health J. 2009 Sep-Oct;15(5):1285-92.

PMID:20214143

Abstract

To assess the serum folate and vitamin B12 status in healthy Iranian adults, we designed a population-based cross-sectional study of 1200 individuals aged 20-80 years. Finally 984 participants (507 men and 477 women) were assessed. The mean serum folate was 4.61 (SD 2.40) ng/mL and the mean serum vitamin B12 level was 265.6 (SD 170.9) pg/mL. Overall 1.0% were folate deficient and 25.8% had low vitamin B12 levels according to the manufacturer's reference ranges (folate < 1.5 ng/mL and vitamin B12 < 160 pg/mL). The mean serum folate and vitamin B12 levels were significantly lower in men. The prevalence of vitamin B12 deficiency was considerably higher than folate deficiency. Implementation of preventive measures seems to be necessary.

摘要

为了评估伊朗健康成年人的血清叶酸和维生素 B12 状况，我们设计了一项基于人群的横断面研究，共纳入了 1200 名 20-80 岁的个体。最终评估了 984 名参与者（507 名男性和 477 名女性）。血清叶酸的平均值为 4.61（SD 2.40）ng/mL，血清维生素 B12 水平的平均值为 265.6（SD 170.9）pg/mL。根据制造商的参考范围（叶酸<1.5ng/mL 和维生素 B12<160pg/mL），总体有 1.0%的人叶酸缺乏，25.8%的人维生素 B12 水平较低。男性的血清叶酸和维生素 B12 水平显著更低。维生素 B12 缺乏的患病率明显高于叶酸缺乏。似乎需要采取预防措施。