Ono Kenji, Nagashima Akira, Yokoyama Erina, Nose Naohiro, Yasumoto Kosei
Department of Chest Surgery, Kitakyushu Municipal Medical Center, Kitakyushu, Japan.
Kyobu Geka. 2010 Mar;63(3):216-9.
The prognosis of patients with bone metastasis from primary lung cancer is poor, and the effective treatment for bone metastasis had not been established. We report a case of more than 6 years survival after a surgical resection of rib metastasis.
A 56-years-old woman underwent right lower lobectomy and mediastinal lymph node dissection for lung cancer (well differentiated adenocarcinoma, pT1N0M0, stage IA) in another hospital in July 1995. In May 2003, the patient suffered right lateral chest pain and the chest computed tomography (CT) showed an osteolytic mass of right 5th rib. Percutaneous ultrasound-guided fine-needle aspiration cytology revealed adenocarcinoma and the tumor was diagnosed as bone metastasis from primary lung cancer. A chest wall resection for bone metastasis of right 5th rib was carried out and she underwent adjuvant chemotherapy. She is presently alive and well without recurrence more than 6 years after chest wall resection.
A resection of bone metastasis from lung cancer may offer the possibility of a long-term survival in selected patients.
原发性肺癌骨转移患者的预后较差,且尚未确立针对骨转移的有效治疗方法。我们报告一例肋骨转移灶手术切除后存活超过6年的病例。
一名56岁女性于1995年7月在另一家医院接受了右下肺叶切除术及纵隔淋巴结清扫术,治疗肺癌(高分化腺癌,pT1N0M0,IA期)。2003年5月,患者出现右侧胸痛,胸部计算机断层扫描(CT)显示右侧第5肋骨有溶骨性肿块。经皮超声引导下细针穿刺细胞学检查显示为腺癌,该肿瘤被诊断为原发性肺癌骨转移。对右侧第5肋骨骨转移灶进行了胸壁切除术,并接受了辅助化疗。目前,她在胸壁切除术后6年多来一直存活且状况良好,无复发。
对肺癌骨转移灶进行切除可能为部分患者提供长期生存的可能性。