Ozdemir Aydan Ongun, Kumbasar Deniz, Dinçer Irem, Atmaca Yusuf
Department of Cardiology, Medicine Faculty of Ankara University, Ankara, Turkey.
Turk Kardiyol Dern Ars. 2010 Jan;38(1):47-9.
Lutembacher syndrome is a rare combination of congenital atrial septal defect (ASD) and acquired mitral stenosis (MS). Although it is traditionally corrected by surgical treatment, both conditions are amenable to transcatheter treatment without the need for surgery. We present a 49-year-old woman with Lutembacher syndrome. On pretreatment transthoracic echocardiography, planimetric mitral valve area was 1.5 cm(2), maximum diastolic gradient was 17 mmHg, and mean diastolic gradient was 9 mmHg. Combined percutaneous treatment was performed including balloon valvuloplasty for MS and closure of the ASD with the Amplatzer septal occluder. The patient was discharged uneventfully. Transthoracic echocardiography performed a week later showed planimetric mitral valve area as 2.1 cm(2), maximum diastolic gradient as 9 mmHg, and mean diastolic gradient as 4 mmHg. Complete closure of the ASD was achieved. Transcatheter treatment may be an effective alternative to surgery in selected patients with Lutembacher syndrome.
鲁登巴赫综合征是一种先天性房间隔缺损(ASD)与后天性二尖瓣狭窄(MS)的罕见组合。尽管传统上通过手术治疗来矫正,但这两种病症都适合经导管治疗而无需进行手术。我们报告一名患有鲁登巴赫综合征的49岁女性。在术前经胸超声心动图检查中,二尖瓣瓣口面积测量值为1.5平方厘米,舒张期最大压力阶差为17毫米汞柱,平均舒张期压力阶差为9毫米汞柱。进行了联合经皮治疗,包括针对二尖瓣狭窄的球囊瓣膜成形术以及使用Amplatzer房间隔封堵器闭合房间隔缺损。患者顺利出院。一周后进行的经胸超声心动图检查显示二尖瓣瓣口面积测量值为2.1平方厘米,舒张期最大压力阶差为9毫米汞柱,平均舒张期压力阶差为4毫米汞柱。房间隔缺损实现了完全闭合。对于部分患有鲁登巴赫综合征的患者,经导管治疗可能是一种有效的手术替代方案。