Wei Ya-Ting, Jiang Shu, Cen Ying
Department of Plastic and Burn Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.
J Craniofac Surg. 2010 Mar;21(2):538-42. doi: 10.1097/SCS.0b013e3181d0243f.
Fibrous dysplasia (FD) is a kind of benign but chronically progressive bone lesion. There is a lack of standard therapy for craniofacial FD because situations are protean. This study aimed at analyzing the clinical characteristics of craniofacial FD and suggesting strategies of treatment according to different situations.
We retrospectively reviewed 81 patients diagnosed as having an FD of the craniofacial region in West China Hospital between 1996 and 2009. The data and follow-up information were collected and analyzed using SPSS 13.0.
Patients were between 5 to 71 years old, with an average age of 23.94 years; 61.73% of the patients were female. The sizes of the lesion range from 1.5 x 2 cm to 15 x 10 cm, most commonly affecting the frontal bones. Painless mass was the most common symptom, and vision loss was the most serious result. Of these patients, 86.4% underwent surgical treatment, 65.4% were followed up, and 86.8% did not show sign of recurrence. The bone defect was best restored with titanium mesh in recent years, and the gross cosmetic results of cranial reconstruction were favorable.
Fibrous dysplasia of the skull in most cases is preferred to be treated with whole excision and immediate reconstruction with titanium mesh.
骨纤维异常增殖症（FD）是一种良性但呈慢性进行性发展的骨病变。由于情况多变，颅面部FD缺乏标准治疗方法。本研究旨在分析颅面部FD的临床特征，并根据不同情况提出治疗策略。
我们回顾性分析了1996年至2009年期间在华西医院被诊断为颅面部FD的81例患者。使用SPSS 13.0收集并分析数据及随访信息。
患者年龄在5至71岁之间，平均年龄为23.94岁；61.73%为女性。病变大小范围从1.5×2厘米至15×10厘米，最常累及额骨。无痛性肿块是最常见症状，视力丧失是最严重后果。这些患者中，86.4%接受了手术治疗，65.4%进行了随访，86.8%未显示复发迹象。近年来，钛网是修复骨缺损的最佳材料，颅骨重建的总体美容效果良好。
大多数情况下，颅骨骨纤维异常增殖症首选全切除并立即用钛网重建治疗。
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