Maeshige N, Fujiwara H, Honda H, Yoshikawa Y, Terashi H, Usami M, Sugimoto M
Division of Nutrition and Metabolism, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan.
J Wound Care. 2010 Feb;19(2):63-8. doi: 10.12968/jowc.2010.19.2.46968.
To evaluate the effect of ultrasound irradiation when used alongside standard care in the treatment of pressure ulcers; outcome measures were reduction in wound size and exudate weight.
Five patients (two male and three female, age range: 76-92 years) with seven ulcers participated in this study. They had National Pressure Ulcer Advisory Panel (NPUAP) stage III or IV pressure ulcers. We conducted an ABABA study (A: standard treatment with dressings that promote a moist wound healing environment; B: ultrasound irradiation administered to the pressure ulcer through the same dressing used in period A; each period lasted 2-4 weeks). Six ulcers each were randomised to either the treatment group or control group. One ulcer was not randomised, but was the first to receive ultrasound in the BABA sequence, with a view to determining if the pilot was feasible. The control group received sham ultrasound in period B. Pulsed ultrasound (20% duty cycle, 0.5W/cm2 on the wound surface, 1MHz or 3MHz, for 10 minutes) was applied five times weekly.
In the treatment group, two ulcers markedly decreased in size after 3-4 weeks of US treatment, one ulcer decreased in size soon after initiation of treatment and one ulcer showed no clear reduction in size. The volume of exudate was greater in period B than A in two ulcers that reduced markedly in size after 3-4 weeks of US treatment. None of the ulcers in the control group decreased markedly in size.
This pilot study suggests that US used alongside standard treatment might promote the healing of pressure ulcers. However, larger studies are required to determine the efficacy and mechanism of US treatment for PUs.
None.
评估超声照射联合标准护理在治疗压疮中的效果；观察指标为伤口大小和渗出物重量的减少情况。
五名患者（两名男性和三名女性，年龄范围：76 - 92岁）患有七处压疮，参与了本研究。他们患有美国国家压疮咨询小组（NPUAP）III期或IV期压疮。我们进行了一项ABABA研究（A：使用促进伤口湿润愈合环境的敷料进行标准治疗；B：通过与A期相同的敷料对压疮进行超声照射；每个阶段持续2 - 4周）。六处溃疡分别随机分为治疗组或对照组。一处溃疡未随机分组，但在BABA序列中首先接受超声治疗，以确定该试验是否可行。对照组在B期接受假超声治疗。每周进行五次脉冲超声治疗（占空比20%，伤口表面功率0.5W/cm²，频率1MHz或3MHz，持续10分钟）。
在治疗组中，两处溃疡在超声治疗3 - 4周后大小明显减小，一处溃疡在治疗开始后不久大小减小，一处溃疡大小无明显减小。在超声治疗3 - 4周后大小明显减小的两处溃疡中，B期的渗出物量比A期多。对照组中没有溃疡大小明显减小。
这项初步研究表明，超声联合标准治疗可能促进压疮的愈合。然而，需要更大规模的研究来确定超声治疗压疮的疗效和机制。
无。
