生物学中的隐马尔可夫模型。
Hidden Markov models in biology.
作者信息
Vogl Claus, Futschik Andreas
机构信息
Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.
出版信息
Methods Mol Biol. 2010;609:241-53. doi: 10.1007/978-1-60327-241-4_14.
PMID:20221923
Abstract
Markov and Hidden Markov models (HMMs) are introduced using examples from linkage mapping and sequence analysis. In the course, the forward-backward, the Viterbi, the Baum-Welch (EM) algorithm, and a Metropolis sampling scheme are presented.
摘要
通过连锁图谱分析和序列分析的示例介绍了马尔可夫模型和隐马尔可夫模型（HMM）。在本课程中，还介绍了前向-后向算法、维特比算法、鲍姆-韦尔奇（EM）算法以及一种 metropolis 采样方案。
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