Rajkumar T, Soumittra N, Vidubala E, Sridevi V, Mahajan V, Ramanan Sg, Vijaya S
Dept, of Molecular Oncology, Cancer Institute (WIA), Adyar, Chennai - 600020, India.
Hered Cancer Clin Pract. 2005 Nov 15;3(4):165-70. doi: 10.1186/1897-4287-3-4-165.
Hereditary cancers are thought to account for around 5% of cancers, particularly breast/ovarian and colorectal cancers. In India there is a paucity of data on hereditary cancers and the mutations in some of the common genes linked to hereditary cancers, such as BRCA1, BRCA2, hMSH2 and hMLH1. The country's first comprehensive hereditary cancer clinic was established in February 2002. The article describes the organization and running of the Clinic. It also discusses some of the social issues relevant to the given population in running the Hereditary Cancer Clinic.
遗传性癌症被认为约占所有癌症的5%,尤其是乳腺癌/卵巢癌和结直肠癌。在印度,关于遗传性癌症以及与遗传性癌症相关的一些常见基因(如BRCA1、BRCA2、hMSH2和hMLH1)突变的数据匮乏。该国首个综合性遗传性癌症诊所于2002年2月成立。本文描述了该诊所的组织和运营情况。还讨论了在运营遗传性癌症诊所时与特定人群相关的一些社会问题。